Evidence map›Paper›PMID 34638777›Full record

ArticleInternational journal of molecular sciences2021

SUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification.

Helen M Bellchambers, Kristen S Barratt, Koula E M Diamand, Ruth M Arkell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Neural Crest Development in Health and Disease.International journal of molecular sciences · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Helen M BellchambersEarly Mammalian Development Laboratory, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0002-3164-4197
Kristen S BarrattEarly Mammalian Development Laboratory, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0003-0531-5231
Koula E M DiamandEarly Mammalian Development Laboratory, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0002-3436-5679
Ruth M ArkellEarly Mammalian Development Laboratory, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Australian National University · AU

Funding

Sylvia and Charles Viertel Charitable Foundation Senior Medical Fellowship
6 · The paper itself

Abstract

The mechanisms of neural crest cell induction and specification are highly conserved among vertebrate model organisms, but how similar these mechanisms are in mammalian neural crest cell formation remains open to question. The zinc finger of the cerebellum 1 (ZIC1) transcription factor is considered a core component of the vertebrate gene regulatory network that specifies neural crest fate at the neural plate border. In mouse embryos, however,

Indexed as

SumoylationTranscription, GeneticWnt Signaling PathwayAnimalsEmbryo, MammalianForkhead Transcription FactorsMiceMice, TransgenicNeural CrestRepressor ProteinsTranscription FactorsForkhead Transcription FactorsFoxd3 protein, mouseRepressor ProteinsTranscription Factorsco-factorFoxd3mouse neural crest cellpost-translational modificationTCFtranscription factorZIC

Identifiers

PMID34638777
PMCPMC8509024
OpenAlexW3204283839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.