Evidence map›Paper›PMID 34638776›Full record

ReviewInternational journal of molecular sciences2021

Phage Therapy as a Focused Management Strategy in Aquaculture.

José Ramos-Vivas, Joshua Superio, Jorge Galindo-Villegas, Félix Acosta

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Bacteriophages AgainstViruses · 2026
    Review
  2. Article
  3. Review
  4. Avian PathogenicVeterinary sciences · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Frontiers in veterinary science · 2025
    Article
  15. SXP01: a novel bacteriophage for combatingFrontiers in microbiology · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

José Ramos-VivasGrupo de Investigación en Acuicultura, Universidad de Las Palmas de Gran Canaria, 35214 Las Palmas de Gran Canaria, Spain.
Joshua SuperioFaculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway.ORCID 0000-0002-8509-2463
Jorge Galindo-VillegasFaculty of Biosciences and Aquaculture, Nord University, 8049 Bodø, Norway.ORCID 0000-0002-4250-2477
Félix AcostaGrupo de Investigación en Acuicultura, Universidad de Las Palmas de Gran Canaria, 35214 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-1098-7529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic bacteriophages, commonly called as phages, are a promising potential alternative to antibiotics in the management of bacterial infections of a wide range of organisms including cultured fish. Their natural immunogenicity often induces the modulation of a variated collection of immune responses within several types of immunocytes while promoting specific mechanisms of bacterial clearance. However, to achieve standardized treatments at the practical level and avoid possible side effects in cultivated fish, several improvements in the understanding of their biology and the associated genomes are required. Interestingly, a particular feature with therapeutic potential among all phages is the production of lytic enzymes. The use of such enzymes against human and livestock pathogens has already provided in vitro and in vivo promissory results. So far, the best-understood phages utilized to fight against either Gram-negative or Gram-positive bacterial species in fish culture are mainly restricted to the

Indexed as

MyoviridaePhage TherapyPodoviridaeSiphoviridaeAnimalsBacterial InfectionsHumansaquaculturebacteriophagesdisease managementfishimmunologylytic enzymespathogens

Identifiers

PMID34638776
PMCPMC8508683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.