Evidence map›Paper›PMID 34638764›Full record

ArticleInternational journal of molecular sciences2021

FluCell-SELEX Aptamers as Specific Binding Molecules for Diagnostics of the Health Relevant Gut Bacterium

Heinz Fabian Raber, Dennis Horst Kubiczek, Nicholas Bodenberger, Ann-Kathrin Kissmann, Deena D'souza, Hu Xing, Daniel Mayer, Pengfei Xu, Uwe Knippschild, Barbara Spellerberg and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  14. A Polyclonal SELEX Aptamer Library Allows Differentiation ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  15. A Polyclonal Aptamer Library for the Specific Binding of the Gut BacteriumInternational journal of molecular sciences · 2022
    Article
  16. Aptamers: Functional-Structural Studies and Biomedical Applications.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Heinz Fabian RaberInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Dennis Horst KubiczekInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Nicholas BodenbergerInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Ann-Kathrin KissmannInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Deena D'souzaInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Hu XingInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Daniel MayerInstitute for Medical Microbiology and Hygiene, University Hospital Ulm, 89081 Ulm, Germany.
Pengfei XuDepartment of General and Visceral Surgery, Surgery Center, Ulm University, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Uwe KnippschildDepartment of General and Visceral Surgery, Surgery Center, Ulm University, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Barbara SpellerbergInstitute for Medical Microbiology and Hygiene, University Hospital Ulm, 89081 Ulm, Germany.ORCID 0000-0001-7552-8764
Tanja WeilMax Planck Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.ORCID 0000-0002-5906-7205
Frank RosenauInstitute for Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419
Universität Ulm · DEUniversity Hospital Ulm · DEMax Planck Institute for Polymer Research · DE

Funding

Baden-Württemberg Stiftung BiofMO_005Horizon 2020 Framework Programme 686271Ministry of Science, Research and the Arts of Baden-Württemberg 7533-10-5-186A and 7533-10-5-190
6 · The paper itself

Abstract

Based on their unique properties, oligonucleotide aptamers have been named a gift of biological chemistry to life science. We report the development of DNA aptamers as the first high-affinity binding molecules available for fast and rapid labeling of the human gut bacterium

Indexed as

Gastrointestinal MicrobiomeSELEX Aptamer TechniqueAkkermansiaAlzheimer DiseaseAptamers, NucleotideFecesHumansAptamers, NucleotideaptamersbiosensorsFluCell-SELEX

Identifiers

PMID34638764
PMCPMC8509069
OpenAlexW3202869345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.