ReviewInternational journal of molecular sciences2021
Butyric and Citric Acids and Their Salts in Poultry Nutrition: Effects on Gut Health and Intestinal Microbiota.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 88 citations in OpenAlex.
- Dietary supplementation with bacteriophages or acidifiers mitigatesVeterinary and animal science · 2026Article
- Metal Complex-Based Fluorescent Probe for Sensitive Determination of Citric Acid in Food Samples via a Ligand-Exchange Reaction: An Innovative and Sustainable Approach.Journal of fluorescence · 2026Article
- Dietary pyrroloquinoline quinone supplementation improves productive performance, immunity, and intestinal health in late-phase Jingfen No. 6 laying hens.Poultry science · 2026Article
- Effects ofAnimals : an open access journal from MDPI · 2026Article
- Dietary tributyrin attenuates intestinal damage induced by dextran sulfate sodium and modulates growth performance in broilers.Poultry science · 2026Article
- Differential impact of sodium butyrate forms on intestinal morphology, gene expression, and growth performance in broiler chickens under cold stress at high altitude.Veterinary and animal science · 2026Article
- Dietary calcium citrate enhances nutrient digestibility and modulates cecal microbiota function in pre-laying hens.Veterinary world · 2026Article
- Multi-omics analysis reveals that glyceryl monooleate mitigates PEDV-induced intestinal injury in piglets.BMC microbiology · 2026Article
- Beyond Organ Boundaries: Molecular Mechanisms of Hepatic Encephalopathy and Parkinson's Disease from the Perspective of the Gut-Liver-Brain Axis.Research (Washington, D.C.) · 2026Review
- Effects of Sodium Butyrate Forms on Carcass Performance, Pulmonary Hypertension, Metabolic Health and Oxidative-Inflammatory Responses in Broiler Chickens Under Cold Stress at High Altitude.Veterinary medicine and science · 2026Article
- Butyric, lactic, and propionic acids with their salts as natural growth promoters in broilers.Scientific reports · 2025Article
- Impact of Drinking Water Supplemented with Complex Acidifiers on Production Performance, Egg Quality, Physiological and Biochemical Indicators, and Microbial Flora of BIAN Chickens.Life (Basel, Switzerland) · 2025Article
- Improved Eggshell Quality in Aged Hens Through Circadian Gut Microbiota and Metabolite Changes Induced by a 28-h Ahemeral Light Cycle.Animals : an open access journal from MDPI · 2025Article
- Single or Combined Supplementation ofVeterinary sciences · 2025Article
- Effects of N-Carbamylglutamate supplementation on cecal morphology, microbiota composition, and short-chain fatty acids contents of broiler breeder roosters.Scientific reports · 2025Article
- Reciprocal translocation experiments reveal gut microbiome plasticity and host specificity in a Qinghai-Xizang Plateau lizard.Zoological research · 2025Article
- Exploring the Mechanism ofBiology · 2025Article
- The Results of Intestinal Villi of Laying Hens Exposed With Avian PathogenicVeterinary medicine international · 2025Article
- Mechanism and application of yeast and its culture in regulating intestinal antioxidant defense in ruminants.Frontiers in veterinary science · 2025Review
- Impact ofVeterinary sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Intestinal dysfunction of farm animals, such as intestinal inflammation and altered gut microbiota, is the critical problem affecting animal welfare, performance and farm profitability. China has prohibited the use of antibiotics to improve feed efficiency and growth performance for farm animals, including poultry, in 2020. With the advantages of maintaining gut homeostasis, enhancing digestion, and absorption and modulating gut microbiota, organic acids are regarded as promising antibiotic alternatives. Butyric and citric acids as presentative organic acids positively impact growth performance, welfare, and intestinal health of livestock mainly by reducing pathogenic bacteria and maintaining the gastrointestinal tract (GIT) pH. This review summarizes the discovery of butyric acid (BA), citric acid (CA) and their salt forms, molecular structure and properties, metabolism, biological functions and their applications in poultry nutrition. The research findings about BA, CA and their salts on rats, pigs and humans are also briefly reviewed. Therefore, this review will fill the knowledge gaps of the scientific community and may be of great interest for poultry nutritionists, researchers and feed manufacturers about these two weak organic acids and their effects on intestinal health and gut microbiota community, with the hope of providing safe, healthy and nutrient-rich poultry products to consumers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.