Trial report in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors at 6 institutions in 1 country.
Marta LualdiBiochemistry and Functional Proteomics Laboratory, Department of Science and High Technology, Center of Bioinformatics and Center of Neuroscience, University of Insubria, I-21052 Busto Arsizio, Italy.ORCID 0000-0002-0704-3439
Adeena ShafiqueBiochemistry and Functional Proteomics Laboratory, Department of Science and High Technology, Center of Bioinformatics and Center of Neuroscience, University of Insubria, I-21052 Busto Arsizio, Italy.
Edoardo PedriniBiochemistry and Functional Proteomics Laboratory, Department of Science and High Technology, Center of Bioinformatics and Center of Neuroscience, University of Insubria, I-21052 Busto Arsizio, Italy.
Luisa PieroniProteomics and Metabolomic Laboratory, Experimental Neuroscience Department, S. Lucia Foundation IRCCS, I-00168 Rome, Italy.ORCID 0000-0001-7141-1817
Viviana GrecoDepartment of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, I-00168 Rome, Italy.ORCID 0000-0003-4521-0020
Massimo CastagnolaProteomics and Metabolomic Laboratory, Experimental Neuroscience Department, S. Lucia Foundation IRCCS, I-00168 Rome, Italy.
Giorgia CucinaBiochemistry and Functional Proteomics Laboratory, Department of Science and High Technology, Center of Bioinformatics and Center of Neuroscience, University of Insubria, I-21052 Busto Arsizio, Italy.
Lucia CorradoDepartment of Health Sciences, University of Eastern Piedmont "A. Avogadro", I-28100 Novara, Italy.
Alice Di PierroDepartment of Health Sciences, University of Eastern Piedmont "A. Avogadro", I-28100 Novara, Italy.
Fabiola De MarchiDepartment of Translational Medicine, University of Eastern Piedmont "A. Avogadro", I-28100 Novara, Italy.ORCID 0000-0003-0197-1880
Lara CamilloDepartment of Health Sciences, University of Eastern Piedmont "A. Avogadro", I-28100 Novara, Italy.ORCID 0000-0003-2148-3454
Claudia ColombritaDepartment of Neurology-Stroke Unit and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, I-20149 Milan, Italy.
Marianna D'AncaNeurodegenerative Disease Unit, Fondazione Ca' Granda IRCCS, Policlinico Hospital, I-20122 Milan, Italy.ORCID 0000-0001-8625-6506
Tiziana AlberioBiochemistry and Functional Proteomics Laboratory, Department of Science and High Technology, Center of Bioinformatics and Center of Neuroscience, University of Insubria, I-21052 Busto Arsizio, Italy.ORCID 0000-0002-6065-6699
Sandra D'AlfonsoDepartment of Health Sciences, University of Eastern Piedmont "A. Avogadro", I-28100 Novara, Italy.
Mauro FasanoBiochemistry and Functional Proteomics Laboratory, Department of Science and High Technology, Center of Bioinformatics and Center of Neuroscience, University of Insubria, I-21052 Busto Arsizio, Italy.ORCID 0000-0003-0628-5871
University of Insubria · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITFondazione Santa Lucia · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIRCCS Istituto Auxologico Italiano · ITUniversità Cattolica del Sacro Cuore · IT
Funding
Italian Ministry of University PRIN - 201534HNXC
6 · The paper itself
Abstract
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of the corticospinal motor neurons, which ultimately leads to death. The repeat expansion in chromosome 9 open reading frame 72 (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.