SynthesisInternational journal of molecular sciences2021
Role of Neutrophils on the Ocular Surface.
Synthesis in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Association of IL-8 and IL-18 Expression With Histone-Associated NETosis in Aqueous-Deficient and Evaporative Dry Eye Disease.Investigative ophthalmology & visual science · 2026Article
- Smart nanoparticle vaccines integrate nanotechnology artificial intelligence and immunoengineering for precision immunization.Discover nano · 2026Review
- The Immunopathogenesis of uveitis.Frontiers in medicine · 2026Review
- Immune cell dynamics and cytokine regulation in cornea and transplantation.Frontiers in immunology · 2026Review
- Redefining our vision: an updated guide to the ocular immune system.Nature reviews. Immunology · 2024Review
- Proteomic Profiling of Tears in Blau Syndrome Patients in Identification of Potential Disease Biomarkers.International journal of molecular sciences · 2024Article
- Rapid NETosis Is an Effector Mechanism to Combat Ocular Herpes Infection.Investigative ophthalmology & visual science · 2024Article
- Novel potential drugs for the treatment of primary open-angle glaucoma using protein-protein interaction network analysis.Genomics & informatics · 2023Article
- Neutrophil Extracellular Traps and Their Possible Implications in Ocular Herpes Infection.Pathogens (Basel, Switzerland) · 2023Review
- Roles of biomaterials in modulating the innate immune response in ocular therapy.Frontiers in drug delivery · 2023Review
- Autophagy in the normal and diseased cornea.Experimental eye research · 2022Review
- Corneal stromal repair and regeneration.Progress in retinal and eye research · 2022Review
- Review
- Proteases and Their Potential Role as Biomarkers and Drug Targets in Dry Eye Disease and Ocular Surface Dysfunction.International journal of molecular sciences · 2022Review
- Association of Dry Eye Diseases and Auditory Sensitivity.Journal of clinical medicine · 2022Article
- The Differential Reactive Oxygen Species Production of Tear Neutrophils in Response to Various Stimuli In Vitro.International journal of molecular sciences · 2021Article
- Persistent Neutrophil Infiltration and Unique Ocular Surface Microbiome Typify Dupilumab-Associated Conjunctivitis in Patients with Atopic Dermatitis.Ophthalmology scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The ocular surface is a gateway that contacts the outside and receives stimulation from the outside. The corneal innate immune system is composed of many types of cells, including epithelial cells, fibroblasts, natural killer cells, macrophages, neutrophils, dendritic cells, mast cells, basophils, eosinophils, mucin, and lysozyme. Neutrophil infiltration and degranulation occur on the ocular surface. Degranulation, neutrophil extracellular traps formation, called NETosis, and autophagy in neutrophils are involved in the pathogenesis of ocular surface diseases. It is necessary to understand the role of neutrophils on the ocular surface. Furthermore, there is a need for research on therapeutic agents targeting neutrophils and neutrophil extracellular trap formation for ocular surface diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.