Evidence map›Paper›PMID 34638683›Full record

ArticleInternational journal of molecular sciences2021

Role of L-Type Voltage-Gated Calcium Channels in Epileptiform Activity of Neurons.

Denis P Laryushkin, Sergei A Maiorov, Valery P Zinchenko, Sergei G Gaidin, Artem M Kosenkov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Biological psychiatry global open science · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Cation Permeability of Voltage-Gated Hair Cell CaInternational journal of molecular sciences · 2022
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Denis P LaryushkinInstitute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Sergei A MaiorovFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Valery P ZinchenkoFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-1990-3803
Sergei G GaidinFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0003-4221-5344
Artem M KosenkovFederal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Institute of Cell Biophysics of the Russian Academy of Sciences, 142290 Pushchino, Russia.
Institute of Cell Biophysics · RUInstitute of Theoretical and Experimental Biophysics · RU

Funding

Ministry of Science and Higher Education of the Russian Federation AAAA-A20-120101390067-0
6 · The paper itself

Abstract

Epileptic discharges manifest in individual neurons as abnormal membrane potential fluctuations called paroxysmal depolarization shift (PDS). PDSs can combine into clusters that are accompanied by synchronous oscillations of the intracellular Ca

Indexed as

AnimalsCalciumCalcium Channel BlockersCalcium Channels, L-TypeCalcium SignalingCells, CulturedDiltiazemHippocampusMembrane PotentialsNeuronsRatsRats, Sprague-DawleyVerapamilCalciumCalcium Channel BlockersCalcium Channels, L-TypeDiltiazemVerapamildiltiazemepileptiform activityisradipineneuronsnifedipineparoxysmal depolarization shiftverapamilvoltage-gated calcium channels

Identifiers

PMID34638683
PMCPMC8508770
OpenAlexW3204207210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.