ReviewInternational journal of molecular sciences2021
Towards Understanding the Genetic Nature of Vasovagal Syncope.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Advances in diagnosis, management, and long-term outcomes of pediatric vasovagal syncope: a comprehensive review.Frontiers in cardiovascular medicine · 2025Review
- Classification of vasovagal syncope from physiological signals on tilt table testing.Biomedical engineering online · 2024Article
- Genetics and Epigenetics in Complex Diseases.International journal of molecular sciences · 2023Article
- Development of a nomogram model to predict malignant vasovagal syncope in Chinese children.Frontiers in pediatrics · 2023Article
- Novel risk patterns of vasovagal reactions in NZ blood donations complicated by COVID-19 restrictions.Frontiers in public health · 2023Article
- Vasovagal Syncope Is Associated with Variants in Genes Involved in Neurohumoral Signaling Pathways.Genes · 2022Article
- The grand challenge of autonomic disorders.Frontiers in neurology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Syncope, defined as a transient loss of consciousness caused by transient global cerebral hypoperfusion, affects 30-40% of humans during their lifetime. Vasovagal syncope (VVS) is the most common cause of syncope, the etiology of which is still unclear. This review summarizes data on the genetics of VVS, describing the inheritance pattern of the disorder, candidate gene association studies and genome-wide studies. According to this evidence, VVS is a complex disorder, which can be caused by the interplay between genetic factors, whose contribution varies from monogenic Mendelian inheritance to polygenic inherited predisposition, and external factors affecting the monogenic (resulting in incomplete penetrance) and polygenic syncope types.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.