ReviewInternational journal of molecular sciences2021
PIF4 and PIF4-Interacting Proteins: At the Nexus of Plant Light, Temperature and Hormone Signal Integrations.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 56 citations in OpenAlex.
- Antagonistic regulation of PIF4 and HY5 activity by BBX28 regulates thermomorphogenesis.Science advances · 2026Article
- Genome-wide identification of the PIF gene family in broomcorn millet (Panicum miliaceum) highlights PmPIF5 as a candidate regulator of photoperiod responses.BMC plant biology · 2026Article
- Transcription Profiling of Potato Leaves in Response to Heat Stress at Single-Cell Resolution.Plant biotechnology journal · 2026Article
- The miR319/bHLH094 Module Regulates Creeping Bentgrass Thermotolerance by Modulating Auxin Biosynthesis and Signalling Pathway.Plant biotechnology journal · 2026Article
- Convergence between light quality and methyl jasmonate signaling in the regulation of betalain biosynthesis.Frontiers in plant science · 2026Review
- Metabolomic and transcriptomic analyses reveal the mechanisms underlyingFrontiers in genetics · 2026Article
- bZIP factors of the Unfolded Protein Response interact with PIF4 to promote thermomorphogenesis.Nature communications · 2025Article
- Salicylic acid and ROS signaling modulate hypocotyl elongation in darkness via NPR1 and EX1.Science advances · 2025Article
- Review
- The Gene Expression of the Transcription Factors HY5 and HFR1 Is Involved in the Response ofBiology · 2025Article
- The phytochrome-interacting factor PIL13 enhances water use efficiency under fluctuating light and drought resilience in rice and soybean.Communications biology · 2025Article
- PIF4-dependent 2-hydroxymelatonin and 3-hydroxymelatonin biosynthesis is involved in skotomorphogenic seedling growth in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2025Article
- NAC047/052/104 Synergistically Regulate the Dark-Induced Leaf Senescence in Non-Heading Chinese Cabbage.International journal of molecular sciences · 2025Article
- Dwarfs standing tall: breeding towards the 'Yellow revolution' through insights into plant height regulation.Plant molecular biology · 2025Review
- RETINOBLASTOMA-RELATED Has Both Canonical and Noncanonical Regulatory Functions During Thermo-Morphogenic Responses in Arabidopsis Seedlings.Plant, cell & environment · 2025Article
- How Do Arabidopsis Seedlings Sense and React to Increasing Ambient Temperatures?Plants (Basel, Switzerland) · 2025Article
- Genome-Wide Identification of GmPIF Family and Regulatory Pathway Analysis of GmPIF3g in Different Temperature Environments.International journal of molecular sciences · 2025Article
- The PEAPOD repressor complex in Arabidopsis stomatal development.Frontiers in plant science · 2025Review
- Chloroplast Vesiculation and InducedPlant direct · 2025Article
- Specific binding between Arabidopsis thaliana phytochrome-interacting factor 3 (AtPIF3) bHLH and G-box originated prior to embryophyte emergence.BMC plant biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Basic helix-loop-helix (bHLH) family transcription factor PHYTOCHROME INTERACTING FACTOR 4 (PIF4) is necessary for plant adaption to light or high ambient temperature. PIF4 directly associates with plenty of its target genes and modulates the global transcriptome to induce or reduce gene expression levels. However, PIF4 activity is tightly controlled by its interacting proteins. Until now, twenty-five individual proteins have been reported to physically interact with PIF4. These PIF4-interacting proteins act together with PIF4 and form a unique nexus for plant adaption to light or temperature change. In this review, we will discuss the different categories of PIF4-interacting proteins, including photoreceptors, circadian clock regulators, hormone signaling components, and transcription factors. These distinct PIF4-interacting proteins either integrate light and/or temperature cues with endogenous hormone signaling, or control PIF4 abundances and transcriptional activities. Taken together, PIF4 and PIF4-interacting proteins play major roles for exogenous and endogenous signal integrations, and therefore establish a robust network for plants to cope with their surrounding environmental alterations.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.