Evidence map›Paper›PMID 34638600›Full record

ArticleInternational journal of molecular sciences2021

Synthesis and

Mabrouk Horchani, Niels V Heise, Sophie Hoenke, René Csuk, Abdel Halim Harrath, Hichem Ben Jannet, Anis Romdhane

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mabrouk HorchaniLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity, Medicinal Chemistry and Natural Products (LR11ES39), Faculty of Sciences Monastir, University of Monastir, Monastir 5000, Tunisia.
Niels V HeiseOrganic Chemistry, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany.ORCID 0000-0002-6540-6357
Sophie HoenkeOrganic Chemistry, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany.ORCID 0000-0003-0596-5779
René CsukOrganic Chemistry, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany.ORCID 0000-0001-7911-290X
Abdel Halim HarrathCollege of Science, Department of Zoology, King Saud University, Riyad 11451, Saudi Arabia.ORCID 0000-0002-2170-1303
Hichem Ben JannetLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity, Medicinal Chemistry and Natural Products (LR11ES39), Faculty of Sciences Monastir, University of Monastir, Monastir 5000, Tunisia.ORCID 0000-0001-5858-1803
Anis RomdhaneLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity, Medicinal Chemistry and Natural Products (LR11ES39), Faculty of Sciences Monastir, University of Monastir, Monastir 5000, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore a new set of anticancer agents, a novel series of pyrazolo[4,3-

Indexed as

AnimalsAntineoplastic AgentsCell LineCell Line, TumorComputer SimulationCytotoxinsDrug Screening Assays, AntitumorHEK293 CellsHT29 CellsHumansMCF-7 CellsMiceMolecular Docking SimulationNIH 3T3 CellsPyrazolesPyrimidines5-amino-4-cyanopyrazoleAntineoplastic AgentsCytotoxinsPyrazolespyrimidinePyrimidinescytotoxicityin silico dockingpyrazolo-pyrido-pyrimidinesSARtumor cell lines

Identifiers

PMID34638600
PMCPMC8508785

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.