Evidence map›Paper›PMID 34638583›Full record

ArticleInternational journal of molecular sciences2021

Transcriptional Regulation of the Human IL5RA Gene through Alternative Promoter Usage during Eosinophil Development.

Kimberly G Laffey, Jian Du, Adam G Schrum, Steven J Ackerman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kimberly G LaffeyDepartment of Biochemistry and Molecular Genetics (M/C 669), College of Medicine, University of Illinois at Chicago, 2074 Molecular Biology Research Building, 900 S. Ashland Ave., Chicago, IL 60607, USA.
Jian DuDepartment of Biochemistry and Molecular Genetics (M/C 669), College of Medicine, University of Illinois at Chicago, 2074 Molecular Biology Research Building, 900 S. Ashland Ave., Chicago, IL 60607, USA.
Adam G SchrumDepartment of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Steven J AckermanDepartment of Biochemistry and Molecular Genetics (M/C 669), College of Medicine, University of Illinois at Chicago, 2074 Molecular Biology Research Building, 900 S. Ashland Ave., Chicago, IL 60607, USA.
University of Illinois Chicago · USUniversity of Missouri · US

Funding

CYTOKINE REGULATION OF HUMAN EOSINOPHIL GENESR01AI033043 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ACKERMAN, STEVEN JULES · 1992 to 2006
$2.2M
National Institute of Allergy and Infectious Diseases AI033043
6 · The paper itself

Abstract

Regulation of the IL-5 receptor alpha (

Indexed as

Antigens, CD34Base SequenceCCAAT-Enhancer-Binding ProteinsCell DifferentiationCells, CulturedEosinophilsGene Expression RegulationHematopoietic Stem CellsHumansInterleukin-5 Receptor alpha SubunitPromoter Regions, GeneticProtein IsoformsRNA, MessengerTranscription FactorsTranscription, GeneticAntigens, CD34CCAAT-Enhancer-Binding ProteinsIL5RA protein, humanInterleukin-5 Receptor alpha SubunitProtein IsoformsRNA, MessengerTranscription Factorsalternative promoterseosinophil developmentIL-5RA expression

Identifiers

PMID34638583
PMCPMC8549700
OpenAlexW3199978501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.