Evidence map›Paper›PMID 34638560›Full record

ReviewInternational journal of molecular sciences2021

Highlights on the Role of

Shirin Hafezi, Maha Saber-Ayad, Wael M Abdel-Rahman

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Precision immune regulation in KRAS-mutated cancers: the final piece of the puzzle?Journal of experimental & clinical cancer research : CR · 2025
    Review
  6. Review
  7. Review
  8. A Small Molecule with Big Impact: MRTX1133 Targets the KRASG12D Mutation in Pancreatic Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  9. Article
  10. Targeting KRAS in pancreatic cancer.Oncology research · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shirin HafeziSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
Maha Saber-AyadSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-9287-7621
Wael M Abdel-RahmanSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-2149-1043
University of Sharjah · AE

Funding

MBRU-AlMahmeed Research Award 2019 ALM1914University of Sharjah Targeted grant #1801090141-P
6 · The paper itself

Abstract

The most frequent mutated oncogene family in the history of human cancer is the RAS gene family, including

Indexed as

AnimalsCarcinoma, Pancreatic DuctalDiabetes ComplicationsHumansPancreatic NeoplasmsProto-Oncogene Proteins p21(ras)Tumor MicroenvironmentProto-Oncogene Proteins p21(ras)adenocarcinomacancer-associated fibroblastcarcinogenesisimmunotherapypancreasRASstellate cellstumor microenvironmenttyrosine kinase inhibitors

Identifiers

PMID34638560
PMCPMC8508406
OpenAlexW3203534952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.