Evidence map›Paper›PMID 34638549›Full record

ArticleInternational journal of molecular sciences2021

The Bul1/2 Alpha-Arrestins Promote Ubiquitylation and Endocytosis of the Can1 Permease upon Cycloheximide-Induced TORC1-Hyperactivation.

Amalia H Megarioti, Cecilia Primo, George C Kapetanakis, Alexandros Athanasopoulos, Vicky Sophianopoulou, Bruno André, Christos Gournas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. α-Arrestins and Their Functions: From Yeast to Human Health.International journal of molecular sciences · 2022
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Amalia H MegariotiMicrobial Molecular Genetics Laboratory, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Patr. Grigoriou E & 27 Neapoleos St., 15341 Agia Paraskevi, Greece.
Cecilia PrimoMolecular Physiology of the Cell Laboratory, Université Libre de Bruxelles (ULB), IBMM, 6041 Gosselies, Belgium.ORCID 0000-0002-3305-5150
George C KapetanakisMolecular Physiology of the Cell Laboratory, Université Libre de Bruxelles (ULB), IBMM, 6041 Gosselies, Belgium.
Alexandros AthanasopoulosMicrobial Molecular Genetics Laboratory, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Patr. Grigoriou E & 27 Neapoleos St., 15341 Agia Paraskevi, Greece.ORCID 0000-0001-5551-4613
Vicky SophianopoulouMicrobial Molecular Genetics Laboratory, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Patr. Grigoriou E & 27 Neapoleos St., 15341 Agia Paraskevi, Greece.
Bruno AndréMolecular Physiology of the Cell Laboratory, Université Libre de Bruxelles (ULB), IBMM, 6041 Gosselies, Belgium.
Christos GournasMicrobial Molecular Genetics Laboratory, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", Patr. Grigoriou E & 27 Neapoleos St., 15341 Agia Paraskevi, Greece.ORCID 0000-0003-4755-8602
National Centre of Scientific Research "Demokritos" · GRUniversité Libre de Bruxelles · BE

Funding

Fondation Santé E12320Fonds De La Recherche Scientifique - FNRS 746 23655065H2020 Marie Skłodowska-Curie Actions 801505
6 · The paper itself

Abstract

Selective endocytosis followed by degradation is a major mechanism for downregulating plasma membrane transporters in response to specific environmental cues. In

Indexed as

Adaptor Proteins, Signal TransducingAmino Acid Transport Systems, BasicAntifungal AgentsCycloheximideEndocytosisEndosomal Sorting Complexes Required for TransportGene Expression Regulation, FungalProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsUbiquitinationUbiquitin-Protein Ligase ComplexesUbiquitin-Protein LigasesAdaptor Proteins, Signal TransducingAmino Acid Transport Systems, BasicAntifungal AgentsBUL1 protein, S cerevisiaeBUL2 protein, S cerevisiaeCAN1 protein, S cerevisiaeCycloheximideEndosomal Sorting Complexes Required for TransportRSP5 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTORC1 protein complex, S cerevisiaeTranscription FactorsUbiquitin-Protein Ligase ComplexesUbiquitin-Protein Ligasesacidic patcharginineendocytosisNedd4Npr1Target of Rapamycin Complex 1transporterubiquitinα-arrestin

Identifiers

PMID34638549
PMCPMC8508209
OpenAlexW3200710526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.