Evidence map›Paper›PMID 34638500›Full record

ArticleCancers2021

Characteristics of Nephroblastoma/Nephroblastomatosis in Children with a Clinically Reported Underlying Malformation or Cancer Predisposition Syndrome.

Nils Welter, Angelo Wagner, Rhoikos Furtwängler, Patrick Melchior, Leo Kager, Christian Vokuhl, Jens-Peter Schenk, Clemens Magnus Meier, Stefan Siemer, Manfred Gessler and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Nils WelterDepartment of Pediatric Oncology and Hematology, Saarland University, 66421 Homburg, Germany.
Angelo WagnerDepartment of Pediatric Oncology and Hematology, Saarland University, 66421 Homburg, Germany.
Rhoikos FurtwänglerDepartment of Pediatric Oncology and Hematology, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-1967-8343
Patrick MelchiorDepartment of Radiation Oncology, Saarland University, 66421 Homburg, Germany.
Leo KagerSt. Anna Kinderspital, Department of Pediatrics, Medical University Vienna, Kinderspitalgasse 6, 1090 Vienna, Austria.
Christian VokuhlSection of Pediatric Pathology, University of Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.
Jens-Peter SchenkDivision of Pediatric Radiology, Clinic for Diagnostic and Interventional Radiology, University of Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.ORCID 0000-0002-0588-0225
Clemens Magnus MeierDepartment of General, Visceral, Vascular and Pediatric Surgery, Saarland University, 66421 Homburg, Germany.ORCID 0000-0001-5553-6302
Stefan SiemerDepartment of Urology and Pediatric Urology, Saarland University, 66421 Homburg, Germany.
Manfred GesslerDevelopmental Biochemistry and Comprehensive Cancer Center Mainfranken, Theodor-Boveri-Institute/Biocenter, University of Würzburg, 97074 Würzburg, Germany.ORCID 0000-0002-7915-6045
Norbert GrafDepartment of Pediatric Oncology and Hematology, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-2248-323X
Saarland University · DEHeidelberg University · DESt Anna Children's Hospital · ATUniversity of Bonn · DEUniversity of Würzburg · DE

Funding

Deutsche Krebshilfe T2/93/Gr1; 50-2709-Gr2
6 · The paper itself

Abstract

(1) Background: about 10% of Wilms Tumor (WT) patients have a malformation or cancer predisposition syndrome (CPS) with causative germline genetic or epigenetic variants. Knowledge on CPS is essential for genetic counselling. (2) Methods: this retrospective analysis focused on 2927 consecutive patients with WTs registered between 1989 and 2017 in the SIOP/GPOH studies. (3) Results: Genitourinary malformations (GU,

Indexed as

cancer predisposition syndromesclinical malformationsnephroblastomaoutcometumor surveillance

Identifiers

PMID34638500
PMCPMC8507684
OpenAlexW3203597394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.