Evidence map›Paper›PMID 34638428›Full record

ArticleCancers2021

Light Therapy for Cancer-Related Fatigue in (Non-)Hodgkin Lymphoma Survivors: Results of a Randomized Controlled Trial.

Daniëlle E J Starreveld, Laurien A Daniels, Jacobien M Kieffer, Heiddis B Valdimarsdottir, Jessie de Geus, Mirthe Lanfermeijer, Eus J W van Someren, G Esther A Habers, Jos A Bosch, Cécile P M Janus and 15 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 15 institutions in 2 countries.

Daniëlle E J StarreveldDepartment of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-9381-7954
Laurien A DanielsDepartment of Radiotherapy, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands.
Jacobien M KiefferDepartment of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Heiddis B ValdimarsdottirDepartment of Oncological Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA.
Jessie de GeusDepartment of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Mirthe LanfermeijerDepartment of Laboratory Medicine, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-9046-5965
Eus J W van SomerenDepartment of Sleep and Cognition, Netherlands Institute for Neuroscience (An Institute of the Royal Netherlands Academy of Arts and Sciences), 1105 BA Amsterdam, The Netherlands.
G Esther A HabersHealth, Medical, and Neuropsychology Unit, Institute of Psychology, Leiden University, 2333 AK Leiden, The Netherlands.
Jos A BoschDepartment of Clinical Psychology, University of Amsterdam, 1018 WV Amsterdam, The Netherlands.
Cécile P M JanusDepartment of Radiation Oncology, Erasmus MC Cancer Institute, 3015 GD Rotterdam, The Netherlands.
Dick Johan van SpronsenDepartment of Hematology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Roel J de WeijerDepartment of Hematology, University Medical Center Utrecht Cancer Center, 3508 GA Utrecht, The Netherlands.
Erik W A MarijtDepartment of Hematology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Eva de JonghDepartment of Hematology, Albert Schweitzer Hospital, 3318 AT Dordrecht, The Netherlands.
Josée M ZijlstraDepartment of Hematology, Amsterdam University Medical Centers, Cancer Center Amsterdam, 1081 HV Amsterdam, The Netherlands.
Lara H BöhmerDepartment of Hematology, Haga Teaching Hospital, 2545 AA The Hague, The Netherlands.
Margreet HoumesDepartment of Hematology, Admiraal de Ruyter Hospital, 4462 RA Goes, The Netherlands.
Marie José KerstenDepartment of Hematology, Amsterdam University Medical Centers, Cancer Center Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Catharina M KorseDepartment of Laboratory Medicine, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Huub H van RossumDepartment of Laboratory Medicine, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
William H ReddDepartment of Oncological Sciences, Mount Sinai School of Medicine, New York, NY 10029, USA.
Susan K LutgendorfDepartments of Psychological and Brain Sciences, Obstetrics and Gynecology, Urology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA 52240, USA.
Sonia Ancoli-IsraelDepartment of Psychiatry, University of California, San Diego, CA 92093-0737, USA.ORCID 0000-0002-0662-8865
Flora E van LeeuwenDepartment of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-5871-1484
Eveline M A BleikerDepartment of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
The Netherlands Cancer Institute · NLAmsterdam University Medical Centers · NLIcahn School of Medicine at Mount Sinai · USLeiden University Medical Center · NLAdmiraal De Ruyter Ziekenhuis · NLAlbert Schweitzer Ziekenhuis · NLErasmus MC Cancer Institute · NLHaga Hospital · NLLeiden University · NLNetherlands Institute for Neuroscience · NLRadboud University Nijmegen · NLUniversity Medical Center Utrecht · NLUniversity of Amsterdam · NLUniversity of California San Diego · USUniversity of Iowa · US

Funding

KWF Kankerbestrijding NKI 2015-7909
6 · The paper itself

Abstract

purposeTo evaluate the short- and long-term effects of light therapy on fatigue (primary outcome) and sleep quality, depression, anxiety, quality of life, and circadian rhythms (secondary outcomes) in survivors of (non-)Hodgkin lymphoma presenting with chronic cancer-related fatigue.

methodsWe randomly assigned 166 survivors (mean survival 13 years) to a bright white light intervention (BWL) or dim white light comparison (DWL) group. Measurements were completed at baseline (T0), post-intervention (T1), at three (T2), and nine (T3) months follow-up. A mixed-effect modeling approach was used to compare linear and non-linear effects of time between groups.

resultsThere were no significant differences between BWL and DWL in the reduction in fatigue over time. Both BWL and DWL significantly (

conclusionsBWL was not superior in reducing fatigue compared to DWL in HL and DLBCL survivors. Remarkably, the total sample showed clinically relevant and persistent improvements on fatigue not commonly seen in longitudinal observational studies in these survivors.

Indexed as

cancer-related fatiguecircadian rhythmslight therapyrandomized controlled trialsleep

Identifiers

PMID34638428
PMCPMC8508131
OpenAlexW3204524863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.