Evidence map›Paper›PMID 34638308›Full record

ReviewCancers2021

The Gut Microbiome and Cancer Immunotherapy: Can We Use the Gut Microbiome as a Predictive Biomarker for Clinical Response in Cancer Immunotherapy?

Byeongsang Oh, Frances Boyle, Nick Pavlakis, Stephen Clarke, Thomas Eade, George Hruby, Gillian Lamoury, Susan Carroll, Marita Morgia, Andrew Kneebone and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Microbiome and cancer immunotherapy: a bibliometric analysis.Journal of the Egyptian National Cancer Institute · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Tumor Microenvironment in Melanoma-Characteristic and Clinical Implications.International journal of molecular sciences · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Immune checkpoint inhibitor-induced diarrhea and colitis: an overview.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Byeongsang OhNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Frances BoyleThe Mater Hospital, North Sydney, NSW 2065, Australia.
Nick PavlakisNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.ORCID 0000-0002-1738-0316
Stephen ClarkeNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Thomas EadeNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
George HrubyNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Gillian LamouryNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.ORCID 0000-0001-9290-0193
Susan CarrollNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Marita MorgiaNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Andrew KneeboneNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Mark StevensNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.ORCID 0000-0001-6009-3470
Wen LiuUniversity of Kansas Medical Center, Kansas City, KS 66160-7601, USA.
Brian CorlessNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Mark MolloyBowel Cancer and Biomarker Laboratory, Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2065, Australia.ORCID 0000-0003-4679-5868
Benjamin KongNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
Towia LibermannHarvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-4006-8179
David RosenthalHarvard Medical School, Boston, MA 02115, USA.
Michael BackNorthern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.
The University of Sydney · AUMater Health Services · AUBeth Israel Deaconess Medical Center · USHarvard University · USRoyal North Shore Hospital · AUUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancergut microbiomeimmune checkpoint inhibitorimmunotherapy

Identifiers

PMID34638308
PMCPMC8508052
OpenAlexW3203589616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.