Evidence map›Paper›PMID 34638295›Full record

ArticleCancers2021

Targeted Sequencing Revealed Distinct Mutational Profiles of Ocular and Extraocular Sebaceous Carcinomas.

Hee Young Na, Jeong Hwan Park, Sun Ah Shin, Sejoon Lee, Heonyi Lee, Heejoon Chae, HoKyung Choung, Namju Kim, Jin-Haeng Chung, Ji Eun Kim

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Hee Young NaDepartment of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0002-2464-0665
Jeong Hwan ParkDepartment of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0003-4522-9928
Sun Ah ShinDepartment of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.
Sejoon LeePrecision Medicine Center, Seoul National University Bundang Hospital, Seongnam 13620, Korea.
Heonyi LeeBioinformatics Collaboration Unit, Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul 03722, Korea.
Heejoon ChaeDivision of Computer Science, Sookmyung Women's University, Seoul 04312, Korea.ORCID 0000-0002-0960-5829
HoKyung ChoungDepartment of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul 07067, Korea.
Namju KimDepartment of Ophthalmology, Seoul National University Bundang Hospital, Seongnam 13620, Korea.
Jin-Haeng ChungDepartment of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.
Ji Eun KimDepartment of Pathology, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0002-2156-9875
Seoul National University · KRSeoul National University Bundang Hospital · KRSookmyung Women's University · KRYonsei University · KR

Funding

Seoul National University Bundang Hospital Research Fund 13-2017-012
6 · The paper itself

Abstract

The biological behavior of sebaceous carcinoma (SeC) is relatively indolent; however, local invasion or distant metastasis is sometimes reported. Nevertheless, a lack of understanding of the genetic background of SeC makes it difficult to apply effective systemic therapy. This study was designed to investigate major genetic alterations in SeCs in Korean patients. A total of 29 samples, including 20 ocular SeCs (SeC-Os) and 9 extraocular SeCs (SeC-EOs), were examined. Targeted next-generation sequencing tests including 171 cancer-related genes were performed.

Indexed as

geneticsnext-generation sequencingsebaceous carcinoma

Identifiers

PMID34638295
PMCPMC8508046
OpenAlexW3202096672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.