Evidence map›Paper›PMID 34638276›Full record

ArticleCancers2021

Clinical Outcomes Following Re-Operations for Intracranial Meningioma.

George E Richardson, Conor S Gillespie, Mohammad A Mustafa, Basel A Taweel, Ali Bakhsh, Siddhant Kumar, Sumirat M Keshwara, Tamara Ali, Bethan John, Andrew R Brodbelt and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

George E RichardsonInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0001-5610-451X
Conor S GillespieInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0002-9153-3077
Mohammad A MustafaInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0002-7703-0174
Basel A TaweelInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.
Ali BakhshInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.
Siddhant KumarInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.
Sumirat M KeshwaraInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.
Tamara AliDepartment of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool L9 7LJ, UK.
Bethan JohnDepartment of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool L9 7LJ, UK.
Andrew R BrodbeltDepartment of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool L9 7LJ, UK.
Emmanuel ChavredakisDepartment of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool L9 7LJ, UK.
Samantha J MillsDepartment of Neuroradiology, The Walton Centre NHS Foundation Trust, Liverpool L9 7LJ, UK.ORCID 0000-0002-1017-6654
Chloë MayDepartment of Clinical Oncology, Clatterbridge Cancer Trust, Liverpool CH63 4JY, UK.
Christopher P MillwardInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0001-7727-1157
Abdurrahman I IslimInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0001-9621-043X
Michael D JenkinsonInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0003-4587-2139
University of Liverpool · GBClatterbridge Cancer Centre NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcomes following re-operation for meningioma are poorly described. The aim of this study was to identify risk factors for a performance status outcome following a second operation for a recurrent meningioma. A retrospective, comparative cohort study was conducted. The primary outcome measure was World Health Organization performance. Secondary outcomes were complications, and overall and progression free survival (OS and PFS respectively). Baseline clinical characteristics, tumor details, and operation details were collected. Multivariable binary logistic regression was used to identify risk factors for performance status outcome following a second operation. Between 1988 and 2018, 712 patients had surgery for intracranial meningiomas, 56 (7.9%) of which underwent a second operation for recurrence. Fifteen patients (26.8%) had worsened performance status after the second operation compared to three (5.4%) after the primary procedure (

Indexed as

complicationsmeningiomaoutcomesrecurrencere-operationssurgery

Identifiers

PMID34638276
PMCPMC8507983
OpenAlexW3204747600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.