Evidence map›Paper›PMID 34638226›Full record

ReviewCancers2021

Artificial Intelligence in Thyroid Field-A Comprehensive Review.

Fabiano Bini, Andrada Pica, Laura Azzimonti, Alessandro Giusti, Lorenzo Ruinelli, Franco Marinozzi, Pierpaolo Trimboli

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Thy-DAMP: deep artificial neural network model for prediction of thyroid cancer mortality.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Targeted sequencing of DNA/RNA combined with radiomics predicts lymph node metastasis of papillary thyroid carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Fabiano BiniDepartment of Mechanical and Aerospace Engineering, Sapienza-University of Rome, 00184 Rome, Italy.ORCID 0000-0002-5641-1189
Andrada PicaDepartment of Mechanical and Aerospace Engineering, Sapienza-University of Rome, 00184 Rome, Italy.ORCID 0000-0002-6877-4120
Laura AzzimontiDalle Molle Institute for Artificial Intelligence (IDSIA), Università della Svizzera Italiana (USI), Scuola Universitaria Professionale della Svizzera Italiana (SUPSI), Polo Universitario Lugano-Campus Est, 6962 Lugano-Viganello, Switzerland.
Alessandro GiustiDalle Molle Institute for Artificial Intelligence (IDSIA), Università della Svizzera Italiana (USI), Scuola Universitaria Professionale della Svizzera Italiana (SUPSI), Polo Universitario Lugano-Campus Est, 6962 Lugano-Viganello, Switzerland.
Lorenzo RuinelliInformation and Communications Technology, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Franco MarinozziDepartment of Mechanical and Aerospace Engineering, Sapienza-University of Rome, 00184 Rome, Italy.
Pierpaolo TrimboliServizio di Endocrinologia e Diabetologia, Ospedale Regionale di Lugano e Mendrisio, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0002-2125-4937
Sapienza University of Rome · ITUniversity of Applied Sciences and Arts of Southern Switzerland · CHEnte Ospedaliero Cantonale · CHOspedale regionale di Lugano · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) uses mathematical algorithms to perform tasks that require human cognitive abilities. AI-based methodologies, e.g., machine learning and deep learning, as well as the recently developed research field of radiomics have noticeable potential to transform medical diagnostics. AI-based techniques applied to medical imaging allow to detect biological abnormalities, to diagnostic neoplasms or to predict the response to treatment. Nonetheless, the diagnostic accuracy of these methods is still a matter of debate. In this article, we first illustrate the key concepts and workflow characteristics of machine learning, deep learning and radiomics. We outline considerations regarding data input requirements, differences among these methodologies and their limitations. Subsequently, a concise overview is presented regarding the application of AI methods to the evaluation of thyroid images. We developed a critical discussion concerning limits and open challenges that should be addressed before the translation of AI techniques to the broad clinical use. Clarification of the pitfalls of AI-based techniques results crucial in order to ensure the optimal application for each patient.

Indexed as

artificial intelligencedeep learningdiagnosismachine learningmedical imagingpredictionradiomicsthyroid neoplasm

Identifiers

PMID34638226
PMCPMC8507551
OpenAlexW3203940270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.