Evidence map›Paper›PMID 34637670›Full record

ArticleBioengineered2021

Circular RNA circ_0090231 promotes atherosclerosis in vitro by enhancing NLR family pyrin domain containing 3-mediated pyroptosis of endothelial cells.

Yishan Ge, Wenwu Liu, Wei Yin, Xuebin Wang, Jie Wang, Xiaoqing Zhu, Shengkai Xu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Circular RNAs in vascular diseases.Frontiers in cardiovascular medicine · 2023
    Review
  13. Review
  14. Regulation of Pyroptosis by ncRNA: A Novel Research Direction.Frontiers in cell and developmental biology · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yishan GeDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Wenwu LiuDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Wei YinDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Xuebin WangDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Jie WangDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Xiaoqing ZhuDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Shengkai XuDepartment of Cardiology, Affiliated Suzhou Science and Technology City Hospital of Nanjing Medical University, Suzhou, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is an inflammatory disease caused by multiple factors. Multiple circRNAs are involved in the development of AS. The present study focusses on delineating the role of circ_0090231 in AS. Human aortic endothelial cells (HAECs) were treated with oxidized low-density lipoprotein (ox-LDL) to construct an

Indexed as

ApoptosisAtherosclerosisCell ProliferationCells, CulturedCell SurvivalCytokinesHumansHuman Umbilical Vein Endothelial CellsLipoproteins, LDLMicroRNAsNLR Family, Pyrin Domain-Containing 3 ProteinPyroptosisRNA, CircularSignal TransductionCytokinesLipoproteins, LDLMicroRNAsNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanoxidized low density lipoproteinRNA, CircularAtherosclerosiscirc_0090231miR-635NLRP3pyroptosis

Identifiers

PMID34637670
PMCPMC8809982
OpenAlexW3205720499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.