Evidence map›Paper›PMID 34637475›Full record

ArticlePloS one2021

Practical considerations for Ultraviolet-C radiation mediated decontamination of N95 respirator against SARS-CoV-2 virus.

Guillaume R Golovkine, Allison W Roberts, Chase Cooper, Sebastian Riano, Angela M DiCiccio, Daniel L Worthington, Jeffrey P Clarkson, Michael Krames, Jianping Zhang, Ying Gao and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evaluation of the effectiveness of UV-C dose for photoinactivation of SARS-CoV-2 in contaminated N95 respirator, surgical and cotton fabric masks.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Guillaume R GolovkineDepartment of Molecular and Cell Biology, University of California, Berkeley, California, United States of America.ORCID 0000-0001-8388-5892
Allison W RobertsDepartment of Molecular and Cell Biology, University of California, Berkeley, California, United States of America.
Chase CooperVerily Life Sciences, South San Francisco, California, United States of America.
Sebastian RianoVerily Life Sciences, South San Francisco, California, United States of America.
Angela M DiCiccioVerily Life Sciences, South San Francisco, California, United States of America.
Daniel L WorthingtonVerily Life Sciences, South San Francisco, California, United States of America.
Jeffrey P ClarksonVerily Life Sciences, South San Francisco, California, United States of America.
Michael KramesArkesso, LLC, Palo Alto, California, United States of America.ORCID 0000-0001-8545-851X
Jianping ZhangBolb Inc, Livermore, California, United States of America.ORCID 0000-0003-1434-988X
Ying GaoBolb Inc, Livermore, California, United States of America.
Ling ZhouBolb Inc, Livermore, California, United States of America.
Scott B BieringSchool of Public Health, University of California, Berkeley, California, United States of America.
Sarah A StanleyDepartment of Molecular and Cell Biology, University of California, Berkeley, California, United States of America.ORCID 0000-0002-4182-9048
University of California, Berkeley · USLawrence Livermore National Security · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decontaminating N95 respirators for reuse could mitigate shortages during the COVID-19 pandemic. Although the United States Center for Disease Control has identified Ultraviolet-C irradiation as one of the most promising methods for N95 decontamination, very few studies have evaluated the efficacy of Ultraviolet-C for SARS-CoV-2 inactivation. In addition, most decontamination studies are performed using mask coupons that do not recapitulate the complexity of whole masks. We sought to directly evaluate the efficacy of Ultraviolet-C mediated inactivation of SARS-CoV-2 on N95 respirators. To that end we created a portable UV-C light-emitting diode disinfection chamber and tested decontamination of SARS-CoV-2 at different sites on two models of N95 respirator. We found that decontamination efficacy depends on mask model, material and location of the contamination on the mask. Our results emphasize the need for caution when interpreting efficacy data of UV-C decontamination methods.

Indexed as

DecontaminationDisinfectionMasksN95 RespiratorsUltraviolet RaysEquipment Reuse

Identifiers

PMID34637475
PMCPMC8509861
OpenAlexW3205996504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.