Evidence map›Paper›PMID 34637074›Full record

ArticleMolecular and cellular biochemistry2022

Therapeutic potential of Smilax fluminensis ethanolic extract: antitumoral activity in murine melanoma cells.

Bruna Z Fetter, Doroty M Dourado, Danielle Bogo, Rosemary Matias, Zaira R Guterres

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Antimelanoma potential of natural compounds derived from plants: a systematic review of in vivo studies of B16 melanoma and its sublines.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Pooled it
  2. Allelochemical Potential ofPlants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Use of Saponinosomes fromACS omega · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bruna Z FetterPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias da Faculdade de Medicina (FAMED)-Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Brazil. bruzfetter@gmail.com.ORCID http://orcid.org/0000-0003-0557-9237
Doroty M DouradoPrograma de Pós-Graduação em Doenças Infecciosas e Parasitárias da Faculdade de Medicina (FAMED)-Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Brazil.
Danielle BogoPrograma de Pós-Graduação em Saúde e Desenvolvimento na Região Centro-Oeste FAMED-Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Brazil.
Rosemary MatiasPrograma de Pós-Graduação em Meio Ambiente e Desenvolvimento da Universidade Anhanguera Uniderp, Campo Grande, Brazil.
Zaira R GuterresInstituto de Química-Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to investigate the in vitro and in vivo antitumor activity of leaves ethanol extract from Smilax fluminensis on murine melanoma. The extract was performed by ethylic alcohol and submitted to classical chemical analysis. Cytotoxicity test were performed on neoplastic cells, where antitumor activity was expressed in GI

Indexed as

AnimalsAntineoplastic Agents, PhytogenicEthanolHT29 CellsHumansMCF-7 CellsMelanoma, ExperimentalMiceNIH 3T3 CellsPC-3 CellsPlant ExtractsSmilaxAntineoplastic Agents, PhytogenicEthanolPlant ExtractsAnticancer activityB16-F10CytotoxicityJapecangaMedicinal plants

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.