ArticleEndocrine connections2021
Triglyceride glycemic index as a biomarker for gestational diabetes mellitus: a systemic review and meta-analysis.
Article in Endocrine connections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic and prognostic value of triglyceride glucose index: a comprehensive evaluation of meta-analysis.Cardiovascular diabetology · 2024Pooled it
- Triglyceride Glycemic Index and Triglyceride/HDL Ratio: Can They be Biomarkers for Insulin Resistance in Euthyroid Women with Hashimoto's Thyroiditis, and Are They Related to Thyroid Function Tests?Endocrine, metabolic & immune disorders drug targets · 2026Article
- Association between triglyceride-glucose index, placental inflammatory cytokines, and perinatal outcomes in preeclampsia.Frontiers in endocrinology · 2026Article
- Metabolic biomarkers in early detection of gestational diabetes mellitus: a prospective diagnostic accuracy study.Frontiers in medicine · 2026Article
- Comparative predictive value of the cholesterol-high-density lipoprotein-glucose index versus the triglyceride-glucose index for gestational dysglycemia: a two-cohort study.Frontiers in endocrinology · 2026Article
- Diagnostic Performance of the Triglyceride-Glucose Index in Screening for Gestational Diabetes Mellitus at 24-28 Weeks of Gestation.Diagnostics (Basel, Switzerland) · 2025Article
- Associations between triglyceride-glucose index in the early trimester of pregnancy and adverse pregnancy outcomes.BMC pregnancy and childbirth · 2025Article
- Association of the Triglyceride-Glucose Index During the First Trimester of Pregnancy with Adverse Perinatal Outcomes.Diagnostics (Basel, Switzerland) · 2025Article
- Association between the new TyG indicator-TyHGB and gestational diabetes mellitus: results from the case-control and prospective cohort studies.Journal of translational medicine · 2025Article
- The first-trimester triglyceride glucose-body mass index is a valuable predictor for adverse pregnancy outcomes.BMC pregnancy and childbirth · 2025Article
- Triglyceride-glucose body mass index and the risk of gestational diabetes mellitus: a population-based cohort study.Frontiers in nutrition · 2025Article
- The role of the triglyceride-glucose index as a biomarker of cardio-metabolic syndromes.Lipids in health and disease · 2024Review
- Second-trimester triglyceride-glucose index to predict adverse outcomes in women with gestational diabetes mellitus: A retrospective multicenter cohort study.Journal of diabetes investigation · 2024Article
- Triglyceride-glucose index in early pregnancy predicts the risk of gestational diabetes: a prospective cohort study.Lipids in health and disease · 2024Article
- Relationships between triglyceride-glucose index and incident gestational diabetes mellitus: a prospective cohort study of a Korean population using publicly available data.Frontiers in public health · 2024Article
- Explore the value of carotid ultrasound radiomics nomogram in predicting ischemic stroke risk in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2024Article
- The Relationship between Coronary Flow Reserve and the TyG Index in Patients with Gestational Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2023Article
- Association of triglyceride-glucose index with the risk of prostate cancer: a retrospective study.PeerJ · 2023Article
- Association of triglyceride-glucose index levels with gestational diabetes mellitus in the US pregnant women: a cross-sectional study.Frontiers in endocrinology · 2023Article
- TyGIS: improved triglyceride-glucose index for the assessment of insulin sensitivity during pregnancy.Cardiovascular diabetology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTriglyceride glycemic (TyG) index is a novel tool for assessing insulin resistance (IR). Recently, TyG index as a potential biomarker for gestational diabetes mellitus (GDM) has been studied, but its performance is yet inconclusive. Thus, we performed this systemic review and meta-analysis to evaluate the performance of TyG index in predicting GDM.
methodsStudies published before March 1, 2021, with comparison of TyG index between GDM patients and healthy controls were retrieved from multiple databases (PubMed, Web of Science, The Cochrane Library, and Embase). The mean difference (MD) of TyG index in GDM patients and healthy controls was pooled using random-effect models.
resultsDifferentiation of TyG index between patients with GDM and controls showed significant results. Overall, there is a four-fold increase in TyG index in GDM patients compared with controls (MD: 0.22, 95% CI: 0.07-0.36, P = 0.003; I2 = 71%, P = 0.009). In subgroup analyses according to gestational time, TyG index in the second trimester predicted GDM with low heterogeneity (MD: 0.26, 95% CI: 0.15-0.37, P < 0.001; I2 = 0%, P = 0.54), while no such correlation was found in the first trimester.
conclusionTyG index, especially in the second trimester, could be a promising biomarker for predicting GDM.
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