Evidence map›Paper›PMID 34636667›Full record

ArticlemSystems2021

The

Bailey Bonet, Yein Ra, Luis M Cantu Morin, Javier Soto Bustos, Jonathan Livny, Matthew F Traxler

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Identification and distribution of a downregulatory signaling alkyloxazole inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Structural basis ofbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bailey BonetDepartment of Plant and Microbial Biology, University of California, Berkeleygrid.47840.3f, Berkeley, California, USA.
Yein RaDepartment of Plant and Microbial Biology, University of California, Berkeleygrid.47840.3f, Berkeley, California, USA.
Luis M Cantu MorinDepartment of Plant and Microbial Biology, University of California, Berkeleygrid.47840.3f, Berkeley, California, USA.
Javier Soto BustosDepartment of Plant and Microbial Biology, University of California, Berkeleygrid.47840.3f, Berkeley, California, USA.
Jonathan LivnyInfectious Disease and Microbiome Program, The Broad Institute of MIT, Cambridge, Massachusetts, USA.
Matthew F TraxlerDepartment of Plant and Microbial Biology, University of California, Berkeleygrid.47840.3f, Berkeley, California, USA.ORCID 0000-0001-8430-595X
University of California, Berkeley · USBroad Institute · US

Funding

Connecting specialized metabolism to social cues in actinomycete bacteriaR35GM128849 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Matthew F Traxler · 2018 to 2026
$3.3M
HHS | National Institutes of Health (NIH) R35GM128849National Science Foundation (NSF) GRFP2015203899NIGMS NIH HHS R35 GM128849Searle Scholars Program SSP-20161411
6 · The paper itself

Abstract

Interspecies interactions are known to activate specialized metabolism in diverse actinomycetes. However, how interspecies cues are sensed and ultimately lead to induction of specialized metabolite biosynthetic gene clusters remains largely unexplored. Using transcriptome sequencing (RNA-seq), we analyzed genes that were transcriptionally induced in the model actinomycete Streptomyces coelicolor during interactions with four different actinomycetes, including genes that encode unusual regulatory systems known as conservons. Deletions in one such system, encoded by the

Indexed as

bacterial interactionsconservongene regulationinterspecies interactionsnatural productsspecialized metabolismStreptomyces

Identifiers

PMID34636667
PMCPMC8510531
OpenAlexW3206145437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.