Evidence map›Paper›PMID 34636666›Full record

ArticlemSystems2021

Expanding the Staphylococcus aureus SarA Regulon to Small RNAs.

Charlotte Oriol, Liviu Cengher, Adhar C Manna, Tony Mauro, Marie-Laure Pinel-Marie, Brice Felden, Ambrose Cheung, Astrid Rouillon

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Linking Virulence and Iron Limitation Response inJournal of proteome research · 2025
    Article
  9. Antibiotics (Basel, Switzerland) · 2025
    Review
  10. Article
  11. Review
  12. Integrated genomic and proteomic analysis of the mouse-adaptedCurrent research in microbial sciences · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Thirty Years of sRNA-Mediated Regulation inInternational journal of molecular sciences · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Charlotte Oriol *Rennes 1 University, INSERM, BRM [Bacterial Regulatory RNAs and Medicine], UMR_S 1230, Rennes, France.ORCID 0000-0001-9974-6678
Liviu Cengher *Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0003-0130-2695
Adhar C MannaDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-4055-2489
Tony MauroRennes 1 University, INSERM, BRM [Bacterial Regulatory RNAs and Medicine], UMR_S 1230, Rennes, France.ORCID 0000-0002-7882-6510
Marie-Laure Pinel-MarieRennes 1 University, INSERM, BRM [Bacterial Regulatory RNAs and Medicine], UMR_S 1230, Rennes, France.ORCID 0000-0001-5128-0741
Brice FeldenRennes 1 University, INSERM, BRM [Bacterial Regulatory RNAs and Medicine], UMR_S 1230, Rennes, France.ORCID 0000-0003-2803-0626
Ambrose CheungDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0001-5120-3949
Astrid RouillonRennes 1 University, INSERM, BRM [Bacterial Regulatory RNAs and Medicine], UMR_S 1230, Rennes, France.ORCID 0000-0001-9280-2577
Inserm · FRDartmouth College · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Dartmouth Cystic Fibrosis Training ProgramT32HL134598 · NHLBI · DARTMOUTH COLLEGE · PI George A. O'Toole · 2017 to 2026
$1.7M
French Ministry of Defense | Direction Générale de l'Armement (DGA)NCI NIH HHS P30 CA023108NHLBI NIH HHS T32 HL134598Université de Rennes 1 (University of Rennes 1)
6 · The paper itself

Abstract

SarA, a transcriptional regulator of Staphylococcus aureus, is a major global regulatory system that coordinates the expression of target genes involved in its pathogenicity. Various studies have identified a large number of SarA target genes, but an in-depth characterization of the

Indexed as

ChIP-SeqRNA-SeqSarA regulonS. aureussRNA

Identifiers

PMID34636666
PMCPMC8510525
OpenAlexW3206510635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.