Evidence map›Paper›PMID 34636248›Full record

ArticleCNS oncology2021

Multi-joint steroid-induced avascular necrosis in a malignant brain tumor patient.

Jessica M Lewis-Gonzalez, Mallika P Patel, Katherine B Peters

Open access · goldAbstract readCase Reports
In one paragraph

Article in CNS oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jessica M Lewis-GonzalezDepartment of Pharmacy, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM 87106, USA.
Mallika P PatelDepartment of Pharmacy, Duke University Medical Center, Durham, NC 27710, USA.
Katherine B PetersDepartment of Neurosurgery & Neurology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0001-5110-3868
Duke Medical Center · USUniversity of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Avascular necrosis (AVN) is a rare but serious adverse event associated with the use of corticosteroids for long durations or at high doses. This case report describes a 47-year-old female patient with low-grade astrocytoma who was initiated on low-dose dexamethasone for symptom management. The patient developed joint pain 1 year after steroid exposure, then was found to have AVN of the hip followed by multiple other joints. This case report highlights the extent to which AVN can occur in patients with brain tumors following a short course of low-dose corticosteroids. Careful evaluation of and monitoring for the development of AVN should occur frequently in patients with brain tumors given the frequent use of corticosteroids for symptom management in this population.

Indexed as

Brain NeoplasmsOsteonecrosisFemaleHumansMiddle AgedSteroidsSteroidsavascular necrosisbrain tumorcorticosteroidsdexamethasonelow-grade astrocytoma

Identifiers

PMID34636248
PMCPMC8610003
OpenAlexW3206528475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.