Evidence map›Paper›PMID 34636194›Full record

ArticleZoological research2021

Hif-1α/Hsf1/Hsp70 signaling pathway regulates redox homeostasis and apoptosis in large yellow croaker (

Sheng-Yu Luo, Jing-Qian Wang, Cheng Liu, Xin-Ming Gao, Yi-Bo Zhang, Jie Ding, Cong-Cong Hou, Jun-Quan Zhu, Bao Lou, Wei-Liang Shen and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Genome-Wide Identification and Expression Analysis ofAnimals : an open access journal from MDPI · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Hypoxia Tolerance of Two Killifish Species.Integrative and comparative biology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Sheng-Yu LuoKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Jing-Qian WangKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Cheng LiuKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Xin-Ming GaoKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Yi-Bo ZhangKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Jie DingKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Cong-Cong HouKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Jun-Quan ZhuKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China. E-mail:zhujunquan@nbu.edu.cn.
Bao LouZhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang 310021, China. E-mail：loubao6577@163.com.
Wei-Liang ShenState Key Laboratory of Large Yellow Croaker Breeding, Ningbo Academy of Oceanology and Fishery, Ningbo, Zhejiang 315012, China.
Xiong-Fei WuState Key Laboratory of Large Yellow Croaker Breeding, Ningbo Academy of Oceanology and Fishery, Ningbo, Zhejiang 315012, China.
Chun-Dan ZhangKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Dao-Jun TangKey Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Ningbo University · CNNingbo Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen is an essential molecule for animal respiration, growth, and survival. Unlike in terrestrial environments, contamination and climate change have led to the frequent occurrence of hypoxia in aquatic environments, thus impacting aquatic animal survival. However, the adaptative mechanisms underlying fish responses to environmental hypoxia remain largely unknown. Here, we used large yellow croaker (

Indexed as

AnimalsApoptosisCell LineCloning, MolecularComputational BiologyGene Expression RegulationHeat Shock Transcription FactorsHomeostasisHypoxia-Inducible Factor 1, alpha SubunitOxidation-ReductionOxygenPerciformesRNA, MessengerSignal TransductionWaterHeat Shock Transcription FactorsHypoxia-Inducible Factor 1, alpha SubunitOxygenRNA, MessengerWaterApoptosisHif-1α/Hsf1/Hsp70HypoxiaLarimichthys croceaRedox homeostasis

Identifiers

PMID34636194
PMCPMC8645889
OpenAlexW3205588589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.