Evidence map›Paper›PMID 34636100›Full record

ArticleDrug and alcohol review2022

Gender and the first-time provision of injection initiation assistance among people who inject drugs across two distinct North American contexts: Tijuana, Mexico and Vancouver, Canada.

Stephanie A Meyers-Pantele, Sonia Jain, Xiaoying Sun, Charles Marks, Kora DeBeck, Kanna Hayashi, Steffanie A Strathdee, Dan Werb

Abstract read
In one paragraph

Article in Drug and alcohol review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie A Meyers-PanteleDepartment of Psychology, San Diego State University, San Diego, USA.
Sonia JainDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, USA.
Xiaoying SunDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, USA.
Charles MarksDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, USA.
Kora DeBeckBritish Columbia Centre on Substance Use, Vancouver, Canada.ORCID 0000-0003-2045-1653
Kanna HayashiBritish Columbia Centre on Substance Use, Vancouver, Canada.ORCID 0000-0003-3843-2928
Steffanie A StrathdeeDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, USA.
Dan WerbDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, USA.ORCID 0000-0003-0614-9386

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Impact of Drug Policy Reform on the HIV Risk Environment among IDUs in TijuanaR37DA019829 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2010 to 2019
$6.7M
Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersU01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2017 to 2024
$4.3M
A Technology-Delivered Peer-to-Peer Support ART Adherence Intervention for HIV+ AdultsR01DA039950 · NIDA · UNIVERSITY OF MINNESOTA · PI HORVATH, KEITH JOSEPH · 2015 to 2019
$3.3M
Preventing HIV by modifying the context for injecting initiationDP2DA040256 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WERB, DANIEL M · 2015 to 2015
$2.3M
CIHR MSH-141971NIDA NIH HHS DP2 DA040256NIDA NIH HHS DP2-DA040256-01NIDA NIH HHS R01 DA039950NIDA NIH HHS R37 DA019829NIDA NIH HHS T32 DA023356NIDA NIH HHS U01 DA021525NIDA NIH HHS U01 DA038886
6 · The paper itself

Abstract

introductionInjection drug use initiation is commonly facilitated by other people who inject drugs (PWID). We investigated how the gender of PWID influences their risk of providing initiation assistance to others across two distinct geo-cultural settings.

methodsData were drawn from two prospective cohorts in Tijuana, Mexico and Vancouver, Canada which conducted semi-annual interviews within the PReventing Injecting by Modifying Existing Responses (PRIMER) study. Participants consisted of PWID who had reported never providing injection initiation assistance at baseline. We then conducted site-specific discrete-time survival analyses assessing the relationship between gender and other relevant covariates (e.g. age and past 6-month sex work) on the risk of the first reported instance of providing initiation assistance.

resultsOf 1988 PWID (Tijuana: n = 596; Vancouver: n = 1392), 256 (43%) and 511 (36.7%) participants were women, and 42 (1.7%) and 78 (1.6%) reported recent injection initiation assistance across a median of three and two follow-up visits, respectively. Women had a lower risk of providing injection initiation assistance for the first time in Tijuana (adjusted hazard ratio = 0.52, 95% confidence interval 0.27-0.99), but not in Vancouver. Gendered pathways, like sex work, were associated with providing initiation assistance for the first time in Vancouver (adjusted hazard ratio = 1.97, 95% confidence interval 1.08-3.61). DISCUSSION AND

conclusionsWomen in Tijuana, but not Vancouver, were less likely to provide first-time initiation assistance among PWID. These results can inform gender- and site-specific prevention efforts aimed at reducing transitions into drug injecting across geographic contexts.

Indexed as

Drug UsersSubstance Abuse, IntravenousCanadaFemaleHumansMexicoProspective StudiesCanadagenderinjection drug useinjection initiationMexicoTijuanaVancouver

Identifiers

PMID34636100
PMCPMC8930605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.