Evidence map›Paper›PMID 34635988›Full record

ArticleObesity surgery2021

Secondary Hyperparathyroidism, Bone Density, and Bone Turnover After Bariatric Surgery: Differences Between Roux-en-Y Gastric Bypass and Sleeve Gastrectomy.

Narriane Chaves Pereira de Holanda, Vanessa Mayana Alves Baad, Louise Rayra Bezerra, Silvane Katarine Medeiros de Lima, Joao Modesto Filho, Caio Chaves de Holanda Limeira, Taisy Cinthia Ferro Cavalcante, Ana Carla Peres Montenegro, Francisco Bandeira

Abstract read
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In one paragraph

Article in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  7. Obesity and Skeletal Fragility.The Journal of clinical endocrinology and metabolism · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Narriane Chaves Pereira de HolandaDepartment of Endocrinology, Federal University of Paraiba, Governador Antônio da Silva Mariz, 601, Portal Do Sol, João Pessoa, PB, CEP: 58046-518, Brazil. narrichaves@gmail.com.ORCID http://orcid.org/0000-0002-5724-8096
Vanessa Mayana Alves BaadPost-Graduated Program in Health Sciences, University of Pernambuco Medical School, Recife, Brazil.
Louise Rayra BezerraDivision of Endocrinology and Diabetes, Agamenon Magalhães Hospital, University of Pernambuco Medical School, Recife, Brazil.
Silvane Katarine Medeiros de LimaDepartment of Endocrinology, Federal University of Paraiba, Governador Antônio da Silva Mariz, 601, Portal Do Sol, João Pessoa, PB, CEP: 58046-518, Brazil.
Joao Modesto FilhoDepartment of Endocrinology, Federal University of Paraiba, Governador Antônio da Silva Mariz, 601, Portal Do Sol, João Pessoa, PB, CEP: 58046-518, Brazil.
Caio Chaves de Holanda LimeiraDepartment of Endocrinology, Federal University of Paraiba, Governador Antônio da Silva Mariz, 601, Portal Do Sol, João Pessoa, PB, CEP: 58046-518, Brazil.
Taisy Cinthia Ferro CavalcantePost-Graduated Program in Health Sciences, University of Pernambuco Medical School, Recife, Brazil.
Ana Carla Peres MontenegroInstituto de Medicina Integral de Pernambuco - IMIP, Recife, Brazil.
Francisco BandeiraPost-Graduated Program in Health Sciences, University of Pernambuco Medical School, Recife, Brazil.
Universidade de Pernambuco · BRUniversidade Federal da Paraíba · BRInstituto de Medicina Integral Professor Fernando Figueira · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBariatric surgery may lead to metabolic bone disease. MATERIALS AND

methodsIn this cross-sectional study, we compared the prevalence of secondary hyperparathyroidism (SHPT), impact on bone mass and turnover markers, and serum leptin after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in 117 patients (91% female, 51% RYGB, age 41.8 ± 6.7 years, time of surgery 4.3 ± 3.4 years) at different times (1-2 years, > 2 and < 5 years and ≥ 5 years). Body composition, bone mineral density (BMD), by dual-energy X-ray absorptiometry, and bone parameters (PTH, serum calcium, 25OHD, alkaline phosphatase (AP), C-telopeptide (CTX)) were analyzed.

resultsPrevalence of SHPT (PTH ≥ 65 pg/ml) was 26%, RYGB > SG (18.4% vs. 7.8%, p = 0.039), despite similar 25OHD and calcium levels. Mean PTH, CTX, and AP were higher in RYGB vs. SG (61.3 ± 29.5 vs 49.5 ± 32.3 pg/ml, p = 0.001; 0.596 ± 0.24 vs. 0.463 ± 0.23 ng/ml; 123.9 ± 60.8 vs. 100.7 ± 62.0 U/l). There were 13.5% decreases in femoral neck BMD in all patients, over the study period. In the last group, the RYGB group showed greater bone loss in total body BMD (1.016 vs. 1.151 g/cm

conclusionOur data suggest a more deleterious role of RYGB on bone remodeling up to 5 years postoperatively in comparison with SG.

Indexed as

Bariatric SurgeryGastric BypassHyperparathyroidism, SecondaryObesity, MorbidAdultBone DensityBone RemodelingCross-Sectional StudiesFemaleGastrectomyHumansMaleMiddle AgedBariatric surgeryBone mineral densityRoux-en-Y gastric bypassSecondary hyperparathyroidismSleeve gastrectomy

Identifiers

PMID34635988
OpenAlexW3207060363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.