Evidence map›Paper›PMID 34635941›Full record

ArticleAbdominal radiology (New York)2022

Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies.

Ying Deng, Zhuoya Yi, Tianhui Zhang, Bing Hu, Linqi Zhang, Kritisha Rajlawot, Sichi Kuang, Bingjun He, Arvin Arani, Jun Chen and 6 more

Open access · greenAbstract read
In one paragraph

Article in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Ying Deng *Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Zhuoya Yi *Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Tianhui ZhangDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Bing HuDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Linqi ZhangDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Kritisha RajlawotDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Sichi KuangDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Bingjun HeDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China.
Arvin AraniDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Jun ChenDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Meng YinDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Phillip RossmanDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Kevin J GlaserDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Sudhakar K VenkateshDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Richard L EhmanDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Jin WangDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, Guangzhou, 510630, Guangdong, People's Republic of China. wangjin3@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-7956-9579
Sun Yat-sen University · CNMayo Clinic · US

Funding

Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
NIBIB NIH HHS R37 EB001981
6 · The paper itself

Abstract

purposeTo demonstrate the feasibility and diagnostic value of high-frequency magnetic resonance elastography (MRE) for evaluation of prostatic disease in patients with lower urinary tract symptoms (LUTS).

methods41 patients who underwent preoperative prostate MRI and MRE with a modified driver were enrolled retrospectively from May 2016 to September 2021. All were included in the assessment of MRE image quality, using a qualitative visual inspection and a quantitative confidence map. 35 patients (prostate cancer (PCa), n = 13; non-PCa, n = 22) undergoing prostatectomy or biopsy were evaluated for the diagnostic performance of stiffness values. The confidence values and the stiffness values were analyzed by one-way analysis of variance (ANOVA) and independent samples T test, respectively. Area under the receiver operating characteristic (AUROC) analysis was performed.

resultsThrough the qualitative analysis, all MRE acquisitions were successful at 60, 90, 120 and 150 Hz. The quantitative confidence values were significantly lower at 60 Hz (0.683 ± 0.055) and 90 Hz (0.762 ± 0.048) than that at 120 Hz (0.814 ± 0.049) and 150 Hz (0.840 ± 0.049), all P < 0.001. The stiffness of PCa was higher than non-PCa at 90 Hz (P = 0.008), 120 Hz (P < 0.001) and 150 Hz (P < 0.001). The AUCs were 0.773, 0.881 and 0.944, respectively.

conclusionProstate MRE using the modified driver is feasible at 60-150 Hz and image quality is better at higher frequencies. Prostate MRE may be useful and helpful to evaluate prostate diseases in patients with LUTS at higher frequencies; however, further study may be warranted with larger population in future.

Indexed as

Elasticity Imaging TechniquesLower Urinary Tract SymptomsFeasibility StudiesHumansMagnetic Resonance ImagingMaleProstateRetrospective StudiesFeasibilityHigh frequencyMagnetic resonance elastographyProstate cancer

Identifiers

PMID34635941
PMCPMC9573768
OpenAlexW3205297434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.