ArticleNature human behaviour2022
Earliest evidence for human use of tobacco in the Pleistocene Americas.
Article in Nature human behaviour, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 48 citations in OpenAlex.
- Industrial Hemp and Tobacco as Multipurpose Crops: Traditional Uses, Contemporary Applications, and Future Perspectives.Plants (Basel, Switzerland) · 2026Review
- Nicotine Exposure During Gestation: From Placental Dysfunction to Long-Term Neurobehavioral Outcomes.Birth defects research · 2026Review
- Article
- How tobacco builds nicotine.Nature chemical biology · 2026Article
- Impact of e-cigarette vaping on the immune system across the body.Physiological reviews · 2026Review
- Nicotine biosynthesis is completed by cryptic activating glucosylation.Nature communications · 2026Article
- Central nervous system stimulants in recreational and medical use.CNS spectrums · 2025Review
- The rodent electronic nicotine delivery system: Apparatus for voluntary nose-only e-cigarette aerosol inhalation.Journal of the experimental analysis of behavior · 2025Article
- Editorial: World No-Tobacco: effects of tobacco and nicotine on the brain.Frontiers in pharmacology · 2025Article
- Towards culturally inclusive healthcare in Peru: Mapping epistemic concepts in contemporary Indigenous Amazonian medicine-Traditional healers' perspectives.PLOS global public health · 2025Article
- Traditional Indigenous-Amazonian Therapy Involving Ceremonial Tobacco Drinking as Medicine: A Transdisciplinary Multi-Epistemic Observational Study.Health education & behavior : the official publication of the Society for Public Health Education · 2024Observational
- Late pleistocene exploitation of Ephedra in a funerary context in Morocco.Scientific reports · 2024Article
- Archaeometabolomics characterizes phenotypic differences in human cortical bone at a molecular level relating to tobacco use.Science advances · 2024Article
- Malignant tumors affecting the head and neck region in ancient times: Comprehensive study of the CRAB Database.Brazilian oral research · 2024Article
- Indigenous-Amazonian Traditional Medicine's Usage of the Tobacco Plant: A Transdisciplinary Ethnopsychological Mixed-Methods Case Study.Plants (Basel, Switzerland) · 2023Article
- nicX-ing bad habits with your microbial friends.Nature metabolism · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current archaeological research on cultigens emphasizes the protracted and intimate human interactions with wild species that defined paths to domestication and, with certain plants, profoundly impacted humanity. Tobacco arguably has had more impact on global patterns in history than any other psychoactive substance, but how deep its cultural ties extend has been widely debated. Excavations at the Wishbone site, directed at the hearth-side activities of the early inhabitants of North America's desert west, have uncovered evidence for human tobacco use approximately 12,300 years ago, 9,000 years earlier than previously documented. Here we detail the preservation context of the site, discuss its cultural affiliation and suggest ways that the tobacco may have been used. The find has implications for our understanding of deep-time human use of intoxicants and its sociocultural intersection with food crop domestication.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.