Evidence map›Paper›PMID 34635814›Full record

ArticleNature chemistry2021

Light-controlled micron-scale molecular motion.

Mario Samperi, Bilel Bdiri, Charlotte D Sleet, Robert Markus, Ajith R Mallia, Lluïsa Pérez-García, David B Amabilino

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 3 countries.

Mario SamperiSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.ORCID http://orcid.org/0000-0003-4362-2574
Bilel BdiriSchool of Chemistry, GSK Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Nottingham, United Kingdom.
Charlotte D SleetSchool of Chemistry, GSK Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Nottingham, United Kingdom.
Robert MarkusSLIM Imaging Unit, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.ORCID http://orcid.org/0000-0003-4535-303X
Ajith R MalliaSchool of Chemistry, GSK Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Nottingham, United Kingdom.
Lluïsa Pérez-GarcíaSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.ORCID http://orcid.org/0000-0003-2031-4405
David B AmabilinoSchool of Chemistry, GSK Carbon Neutral Laboratories for Sustainable Chemistry, University of Nottingham, Nottingham, United Kingdom. david.amabilino@nottingham.ac.uk.ORCID http://orcid.org/0000-0003-1674-8462
University of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The micron-scale movement of biomolecules along supramolecular pathways, mastered by nature, is a remarkable system requiring strong yet reversible interactions between components under the action of a suitable stimulus. Responsive microscopic systems using a variety of stimuli have demonstrated impressive relative molecular motion. However, locating the position of a movable object that travels along self-assembled fibres under an irresistible force has yet to be achieved. Here, we describe a purely supramolecular system where a molecular 'traveller' moves along a 'path' over several microns when irradiated with visible light. Real-time imaging of the motion in the solvated state using total internal reflection fluorescence microscopy shows that anionic porphyrin molecules move along the fibres of a bis-imidazolium gel upon irradiation. Slight solvent changes mean movement and restructuring of the fibres giving microtoroids, indicating control of motion by fibre mechanics with solvent composition. The insight provided here may lead to the development of artificial travellers that can perform catalytic and other functions.

Identifiers

PMID34635814
OpenAlexW3207505191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.