ArticleScientific reports2021
A millisecond passive micromixer with low flow rate, low sample consumption and easy fabrication.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Curvature-driven passive mixing in three-dimensional conical helix micromixers.Microsystems & nanoengineering · 2026Article
- Microfluidic-assisted metal nanoparticle synthesis: emerging trends toward optical sensing applications.RSC advances · 2026Review
- Developing Micro/Nanostructured Fluidic Mixing Technology for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Design and Analysis of a Passive Micromixer Based on Multiple Passages.Micromachines · 2025Article
- Design and Mixing Analysis of a Passive Micromixer with Circulation Promoters.Micromachines · 2024Article
- Mixing Performance of a Passive Micromixer Based on Split-to-Circulate (STC) Flow Characteristics.Micromachines · 2024Article
- Acoustohydrodynamic micromixers: Basic mixing principles, programmable mixing prospectives, and biomedical applications.Biomicrofluidics · 2024Review
- Design and Mixing Analysis of a Passive Micromixer Based on Curly Baffles.Micromachines · 2023Article
- Machine learning-augmented fluid dynamics simulations for micromixer educational module.Biomicrofluidics · 2023Article
- Mixing Performance of a Passive Micromixer Based on Multiple Baffles and Submergence Scheme.Micromachines · 2023Article
- Numerical simulation and parameter optimization of micromixer device using fuzzy logic technique.RSC advances · 2023Article
- Traditional vs. Microfluidic Synthesis of ZnO Nanoparticles.International journal of molecular sciences · 2023Review
- Key Fabrications of Chitosan Nanoparticles for Effective Drug Delivery Using Flow Chemistry Reactors.International journal of nanomedicine · 2023Article
- Mixing Performance of the Modified Tesla Micromixer with Tip Clearance.Micromachines · 2022Article
- Enhancing Mixing Performance in a Rotating Disk Mixing Chamber: A Quantitative Investigation of the Effect of Euler and Coriolis Forces.Micromachines · 2022Article
- Mixing Enhancement of a Passive Micromixer with Submerged Structures.Micromachines · 2022Article
- Label-Free Physical Techniques and Methodologies for Proteins Detection in Microfluidic Biosensor Structures.Biomedicines · 2022Review
- Mixing Performance of a Passive Micro-Mixer with Mixing Units Stacked in Cross Flow Direction.Micromachines · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fast mixing of small volumes of solutions in microfluidic devices is essential for an accurate control and observation of the dynamics of a reaction in biological or chemical studies. It is often, however, a challenging task, as the Reynolds number (Re) in microscopic devices is typically < 100. In this report, we detail a novel mixer based on the "staggered herring bone" (SHB) pattern and "split-recombination" strategies with an optimized geometry, the periodic rotation of the flow structure can be controlled and recombined in a way that the vortices and phase shifts of the flow induce intertwined lamellar structures, thus increasing the contact surface and enhancing mixing. The optimization improves the mixing while using a low flow rate, hence a small volume for mixing and moderate pressure drops. The performances of the patterns were first simulated using COMSOL Multiphysics under different operating conditions. The simulation indicates that at very low flow rate (1-12 µL·min
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