Evidence map›Paper›PMID 34635526›Full record

ArticleBMJ open2021

Prospective randomised trial examining the impact of an educational intervention versus usual care on anticoagulation therapy control based on an SAMe-TT

Arintaya Phrommintikul, Surakit Nathisuwan, Siriluck Gunaparn, Rungroj Krittayaphong, Wanwarang Wongcharoen, Sukhi Sehmi, Samir Mehta, Neil Winkles, Peter Brocklehurst, Jonathan Mathers and 6 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 3 countries.

Arintaya PhrommintikulDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.ORCID 0000-0003-3986-1951
Surakit NathisuwanDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Siriluck GunaparnDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Rungroj KrittayaphongFaculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wanwarang WongcharoenDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Sukhi SehmiClinical Trials Unit, University of Birmingham, Birmingham, UK.
Samir MehtaClinical Trials Unit, University of Birmingham, Birmingham, UK.
Neil WinklesClinical Trials Unit, University of Birmingham, Birmingham, UK.
Peter BrocklehurstClinical Trials Unit, University of Birmingham, Birmingham, UK.
Jonathan MathersInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0001-6651-6286
Sue JowettHealth Economics Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Kate JollyInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Deirdre LaneDepartment of Cardiovascular Health, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0002-5604-9378
G Neil ThomasDepartment of Public Health and Epidemiology, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-2777-1847
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK Gregory.Lip@liverpool.ac.uk.ORCID 0000-0002-7566-1626
TREATS-AF Study Group
Cancer Research UK Clinical Trials Unit · GBUniversity of Birmingham · GBChiang Mai University · THUniversity of Liverpool · GBMahidol University · THSiriraj Hospital · THThailand Center of Excellence in Physics · TH

Funding

Medical Research Council MR/R020892/1
6 · The paper itself

Abstract

introductionThe burden of atrial fibrillation (AF) in Thailand is high and associated with increased morbidity, mortality and healthcare costs. Vitamin K antagonists (eg, warfarin), commonly used for stroke prevention in patients with AF in Thailand, are effective but are often suboptimally controlled. We aim to evaluate the impact of an SAMe-TT METHODS AND ANALYSIS: Multicentre, open-label, parallel-group, randomised controlled trial conducted in Thailand among adult patients (age: 18 years) with AF who are anticoagulant naïve. Patients will be randomised to one of two groups; an SAMe-TT ETHICS AND DISSEMINATION: The study has been approved by the Ethical Review Committee, Ministry of Public Health of Thailand, and registered in the Thai Clinical Trials Registry. The results of this trial will be submitted for publication in a peer-reviewed journal. Participants will be informed via a link to a preview of the publication. A lay summary will also be provided to all participants prior to publication. TRIAL REGISTRATION NUMBER: TCTR20180711003.

Indexed as

Atrial FibrillationStrokeAdolescentAdultAnticoagulantsHumansProspective StudiesQuality of LifeRandomized Controlled Trials as TopicThailandTreatment OutcomeAnticoagulantscardiologyhealth economicsqualitative research

Identifiers

PMID34635526
PMCPMC8506852
OpenAlexW3206310526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.