Evidence map›Paper›PMID 34635501›Full record

ArticleLife science alliance2021

Non-canonical activation of the ER stress sensor ATF6 by

Nnejiuwa U Ibe, Advait Subramanian, Shaeri Mukherjee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Journal of microbiology and biotechnology · 2025
    Article
  2. Article
  3. Deciphering the Link Between ERFrontiers in aging neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nnejiuwa U IbeDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Advait SubramanianDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA.
Shaeri MukherjeeDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA shaeri.mukherjee@ucsf.edu.ORCID 0000-0003-3820-0174

Funding

GENETICS OF EUCARYOTIC AND PROCARYOTIC ORGANISMST32GM007810 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ASHRAFI, KAVEH, NARLIKAR, GEETA J · 1985 to 2020
$15.1M
Subversion of membrane transport pathways by Legionella pneumophilaR01AI118974 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MUKHERJEE, SHAERI · 2016 to 2020
$2.0M
Legionella effectors reveal novel signaling function for the ribosome quality control (RQC) pathwayR01GM140440 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MUKHERJEE, SHAERI · 2021 to 2024
$1.7M
NIAID NIH HHS R01 AI118974NIGMS NIH HHS R01 GM140440NIGMS NIH HHS T32 GM007810
6 · The paper itself

Abstract

The intracellular bacterial pathogen

Indexed as

Activating Transcription Factor 6AnimalsBacterial ProteinsBacterial ToxinsEndoplasmic ReticulumEndoplasmic Reticulum StressGolgi ApparatusHEK293 CellsHeLa CellsHost-Pathogen InteractionsHumansLegionella pneumophilaLegionnaires' DiseaseMiceProtein TransportRAW 264.7 CellsActivating Transcription Factor 6ATF6 protein, humanAtf6 protein, mouseBacterial ProteinsBacterial Toxins

Identifiers

PMID34635501
PMCPMC8507491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.