ArticleVaccine2021
A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States.
Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Unraveling Cardiovascular Risks and Benefits of COVID-19 Vaccines: A Systematic Review.Cardiovascular toxicology · 2025Pooled it
- ST-segment elevation in acute pericarditis and myocardial involvement: electrocardiographic and clinical profiling.Open heart · 2026Observational
- Mechanistic insights into COVID-19 mRNA vaccine-associated myocarditis: a bioinformatics analysis.American journal of translational research · 2025Article
- Cardiac and Neurological Complications Post COVID-19 Vaccination: A Systematic Review of Case Reports and Case Series.Vaccines · 2024Review
- Interleukin-1 Blockers: A Paradigm Shift in the Treatment of Recurrent Pericarditis.Life (Basel, Switzerland) · 2024Review
- Look at the moon not (only) at the fingers.Internal and emergency medicine · 2024Article
- Article
- Review
- Article
- Myocarditis Following COVID-19 Vaccination: Cardiac Imaging Findings in 118 Studies.Tomography (Ann Arbor, Mich.) · 2022Review
- A Deep Learning Algorithm for Detecting Acute Pericarditis by Electrocardiogram.Journal of personalized medicine · 2022Article
- Descriptive Study of Pericarditis Outcomes in Different Etiologies and Risk Factors: A Retrospective Record Review.Cureus · 2022Article
- Temporal relationship of myocarditis and pericarditis following COVID-19 vaccination: A pragmatic approach.International journal of cardiology · 2022Article
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- Rapid resolution of severe pericardial effusion using anakinra in a patient with COVID-19 vaccine-related acute pericarditis relapse: a case report.European heart journal. Case reports · 2022Article
- A Case of Acute Viral Pericarditis Complicated With Pericardial Effusion Induced by Third Dose of COVID Vaccination.Cureus · 2022Article
- Large Hemorrhagic Pericardial Effusion and Cardiac Tamponade Following BNT162b2 (BioNTech/Pfizer) Vaccine.The Brown journal of hospital medicine · 2022Article
- Review
- Cardiovascular complications of COVID-19 vaccines: A review of case-report and case-series studies.Heart & lung : the journal of critical careReview
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).
methodsAll patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.
findingsFive events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.
interpretationAlthough causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity.
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