Evidence map›Paper›PMID 34635196›Full record

ArticleEpidemiology and infection2021

Epidemiological investigations identified an outbreak of Shiga toxin-producing

Saira Butt, Lesley Allison, Bhavita Vishram, David R Greig, Heather Aird, Eisin McDonald, Genna Drennan, Claire Jenkins, Lisa Byrne, Kirsty Licence and 2 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. An outbreak of Shiga toxin-producingEpidemiology and infection · 2026
    Article
  3. Epidemiology of Shiga toxin-producingJournal of medical microbiology · 2025
    Article
  4. National outbreak of Shiga toxin-producingEpidemiology and infection · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Genomic Surveillance of Foodborne Pathogens: Advances and Obstacles.Journal of public health management and practice : JPHMP
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Saira ButtNational Infection Service, Public Health England, London, UK.
Lesley AllisonScottish E. coli O157/STEC Reference Laboratory, Edinburgh, UK.
Bhavita VishramNational Infection Service, Public Health England, London, UK.
David R GreigNational Infection Service, Public Health England, London, UK.
Heather AirdFood, Water & Environmental Microbiology Laboratory, Public Health England, York, UK.
Eisin McDonaldPublic Health Scotland, Meridian Court, 5 Cadogan street, GlasgowG2 6QQ, UK.
Genna DrennanPublic Health Scotland, Meridian Court, 5 Cadogan street, GlasgowG2 6QQ, UK.
Claire JenkinsNational Infection Service, Public Health England, London, UK.ORCID 0000-0001-8600-9169
Lisa ByrneNational Infection Service, Public Health England, London, UK.ORCID 0000-0001-5320-2085
Kirsty LicencePublic Health Scotland, Meridian Court, 5 Cadogan street, GlasgowG2 6QQ, UK.
Alison Smith-PalmerPublic Health Scotland, Meridian Court, 5 Cadogan street, GlasgowG2 6QQ, UK.
Incident Management Team
Public Health England · GBPublic Health Scotland · GB

Funding

Department of Health
6 · The paper itself

Abstract

In October 2019, public health surveillance systems in Scotland identified an increase in the number of reported infections of Shiga toxin-producing Escherichia coli (STEC) O26:H11 involving bloody diarrhoea. Ultimately, across the United Kingdom (UK) 32 cases of STEC O26:H11 stx1a were identified, with the median age of 27 years and 64% were male; six cases were hospitalised. Among food exposures there was an association with consuming pre-packed sandwiches purchased at outlets belonging to a national food chain franchise (food outlet A) [odds ratio (OR) = 183.89, P < 0.001]. The common ingredient identified as a component of the majority of the sandwiches sold at food outlet A was a mixed salad of Apollo and Iceberg lettuce and spinach leaves. Microbiological testing of food and environmental samples were negative for STEC O26:H11, although STEC O36:H19 was isolated from a mixed salad sample taken from premises owned by food outlet A. Contamination of fresh produce is often due to a transient event and detection of the aetiological agent in food that has a short-shelf life is challenging. Robust, statistically significant epidemiological analysis should be sufficient evidence to direct timely and targeted on-farm investigations. A shift in focus from testing the microbiological quality of the produce to investigating the processes and practices through the supply chain and sampling the farm environment is recommended.

Indexed as

Disease OutbreaksAdultDiarrheaEpidemiological MonitoringEscherichia coli InfectionsFast FoodsFemaleFoodborne DiseasesGenome, BacterialHumansMaleSaladsSerogroupShiga-Toxigenic Escherichia coliShiga ToxinUnited KingdomShiga Toxinoutbreakpre-packed sandwichesShiga toxin-producing Escherichia coli serotype O26:H11whole genome sequencing

Identifiers

PMID34635196
PMCPMC8365849
OpenAlexW3191543575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.