Evidence map›Paper›PMID 34635191›Full record

Trial reportPsychological medicine2023

Evidence that a novel transdiagnostic eating disorder treatment reduces reward region response to the thin beauty ideal and high-calorie binge foods.

Eric Stice, Sonja Yokum, Paul Rohde, Jeff Gau, Heather Shaw

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03261050 (Target Engagement of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03261050 nacompletednot on this map

Target Engagement of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders

TypeinterventionalSponsorStanford UniversityRan2017 to 2025Enrolled83ConditionsEating DisorderArmsCounter Attitudinal Therapy, Interpersonal Therapy
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. The Role of the Endocannabinoid System in Binge Eating Disorder.International journal of molecular sciences · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eric SticeDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Sonja YokumOregon Research Institute, Eugene, OR, USA.
Paul RohdeOregon Research Institute, Eugene, OR, USA.
Jeff GauOregon Research Institute, Eugene, OR, USA.
Heather ShawDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Oregon Research Institute · USStanford University · US

Funding

Target Engagment of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders.R33MH111782 · NIMH · STANFORD UNIVERSITY · PI STICE, ERIC M · 2019 to 2023
$2.4M
Target Engagment of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders.R61MH111782 · NIMH · OREGON RESEARCH INSTITUTE · PI STICE, ERIC M · 2017 to 2018
$1.3M
NIMH NIH HHS R33 MH111782NIMH NIH HHS R61 MH111782
6 · The paper itself

Abstract

backgroundFindings from brain imaging studies with small samples can show limited reproducibility. Thus, we tested whether the evidence that a transdiagnostic eating disorder treatment reduces responsivity of brain valuation regions to thin models and high-calorie binge foods, the intervention targets, from a smaller earlier trial emerged when we recruited additional participants.

methodsWomen with DSM-5 eating disorders (

resultsBPT

conclusionsResults from this larger sample provide evidence that BPT reduces valuation of the thin ideal and high-calorie binge foods, the intervention targets, per objective brain imaging data, and produces clinically meaningful reductions in eating pathology.

Indexed as

BeautyFeeding and Eating DisordersBrainFemaleHumansReproducibility of ResultsRewardDissonanceeating disorderstarget engagementtransdiagnostic treatment

Identifiers

PMID34635191
PMCPMC12105730
OpenAlexW3206333356

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.