ReviewJournal of animal science and biotechnology2021
Implication and challenges of direct-fed microbial supplementation to improve ruminant production and health.
Review in Journal of animal science and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
62 citing papers in PubMed, 130 citations in OpenAlex.
- Effects of Oral Administration of Goat Rumen-Derived Bacterial Isolates on In Vitro and In Vivo Rumen Fermentation Characteristics.Animals : an open access journal from MDPI · 2026Article
- Article
- Dietary Supplementation ofMicroorganisms · 2026Article
- The Hungate1000 prokaryotic culture collection encodes a wide variety of bacteriocins.mSystems · 2026Article
- Early supplemental feeding improves post-weaning growth restriction in lambs via the gastrointestinal-metabolic axis.Applied and environmental microbiology · 2026Article
- Effects of Compound Yeast Culture and Yeast Cell Wall Polysaccharide on Intestinal Barrier Function in Mongolian Ram Lambs.Animals : an open access journal from MDPI · 2026Article
- Ruminal tannase-producing bacteria and their effects on growth performance, nutrient digestibility, blood parameters, and rumen bacterial populations in weaning Afshar-Kurdi lambs fed pomegranate peel.Tropical animal health and production · 2026Article
- Effects of inactivatedAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Enhancing the fiber degradation efficiency in dairy cattle rumen through engineered bacterial communities.Microbiome · 2026Article
- Effect of dual bacterial combinations on in vitro nutrient degradability, gas production, methane emission, ruminal fermentation parameters and predictive values in sheep.Scientific reports · 2026Article
- Effects of feeding aTranslational animal science · 2026Article
- Effect of direct-fed microbial feed blocks on blood β-hydroxybutyrate and milk yield in early postpartum buffaloes under field conditions.Veterinary world · 2026Article
- Isolation, characterization, and molecular identification ofJournal of advanced veterinary and animal research · 2026Article
- Direct-fed Microbials (DFM) and Poultry Genomics: A Synergistic Approach to Sustainable Antibiotic Free Farming.Probiotics and antimicrobial proteins · 2026Review
- Effects of direct-fed microbial supplementation on feedlot lamb growth performance, serum biochemical markers, fecal consistency, and fecal microbiota.Translational animal science · 2026Article
- Redefining feed efficiency through the livestock gut microbiome.Frontiers in physiology · 2026Article
- Safe Meat, Smart Science: Biotechnology's Role in Antibiotic Residue Removal.Antibiotics (Basel, Switzerland) · 2025Review
- Gut microbiota profile, potential engineering techniques and its genetic and epigenetic implications in poultry health.World journal of microbiology & biotechnology · 2025Review
- Dietary D-Ribose Supplementation in Sheep: Implications on Rumen, Fecal Microbiota, and Metabolic Function.Microorganisms · 2025Article
- Effects of quadric probiotic blends on rumen fermentation, nutrient degradability, and methane emission in sheep: an in vitro study.AMB Express · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Direct-fed microbials (DFMs) are feed additives containing live naturally existing microbes that can benefit animals' health and production performance. Due to the banned or strictly limited prophylactic and growth promoting usage of antibiotics, DFMs have been considered as one of antimicrobial alternatives in livestock industry. Microorganisms used as DFMs for ruminants usually consist of bacteria including lactic acid producing bacteria, lactic acid utilizing bacteria and other bacterial groups, and fungi containing Saccharomyces and Aspergillus. To date, the available DFMs for ruminants have been largely based on their effects on improving the feed efficiency and ruminant productivity through enhancing the rumen function such as stabilizing ruminal pH, promoting ruminal fermentation and feed digestion. Recent research has shown emerging evidence that the DFMs may improve performance and health in young ruminants, however, these positive outcomes were not consistent among studies and the modes of action have not been clearly defined. This review summarizes the DFM studies conducted in ruminants in the last decade, aiming to provide the new knowledge on DFM supplementation strategies for various ruminant production stages, and to identify what are the potential barriers and challenges for current ruminant industry to adopt the DFMs. Overall literature research indicates that DFMs have the potential to mitigate ruminal acidosis, improve immune response and gut health, increase productivity (growth and milk production), and reduce methane emissions or fecal shedding of pathogens. More research is needed to explore the mode of action of specific DFMs in the gut of ruminants, and the optimal supplementation strategies to promote the development and efficiency of DFM products for ruminants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.