Evidence map›Paper›PMID 34634776›Full record

ArticleThe American journal of tropical medicine and hygiene2021

Ocular Dirofilariasis Case in Thailand Confirmed by Molecular Analysis to Be Caused by Dirofilaria immitis.

Yuwadee Somsap, Patcharaporn Boonroumkaew, Attawit Somsap, Rutchanee Rodpai, Lakkhana Sadaow, Oranuch Sanpool, Wanchai Maleewong, Pewpan M Intapan

Abstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Uncovering a neglected canine filarioid in Asia: First evidence ofCurrent research in parasitology & vector-borne diseases · 2026
    Article
  2. Article
  3. Review
  4. Migratory Soft-Tissue Swelling Owing to Subcutaneous Dirofilariasis.The American journal of tropical medicine and hygiene · 2025
    Article
  5. Article
  6. Article
  7. International journal for parasitology. Parasites and wildlife · 2024
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuwadee SomsapDepartment of Ophthalmology, Chumphae Hospital, Khon Kaen, Thailand.
Patcharaporn BoonroumkaewDepartment of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Attawit SomsapDepartment of Otolaryngology, Chumphae Hospital, Khon Kaen, Thailand.
Rutchanee RodpaiDepartment of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Lakkhana SadaowDepartment of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Oranuch SanpoolDepartment of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Wanchai MaleewongDepartment of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Pewpan M IntapanDepartment of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rare ocular dirofilariasis case along with the clinical characteristics, treatment, and outcome is reported. A whitish roundworm (10.6 cm long and 0.5 mm width) emerged from the pterygium, a triangular tissue growth on the cornea of the eye, of a male patient. The worm had a rounded anterior part, mouth without lips, smooth cuticular surface, and short rounded posterior tail with spicules: these features suggested that it was a male Dirofilaria sp. Molecular identification confirmed that the worm belonged to Dirofilaria immitis. This is the first molecular confirmation that D. immitis is a causative agent of ocular dirofilariasis in Thailand: dirofilariasis is a newly emerging zoonotic disease. Physicians should be alert to zoonotic filarial worms and knowledgeable about treatment of this disease.

Indexed as

AnimalsDirofilaria immitisDirofilariasisDNA, HelminthDNA, MitochondrialElectron Transport Complex IVEye Infections, ParasiticHumansMaleMiddle AgedPhylogenyRNA, RibosomalThailandDNA, HelminthDNA, MitochondrialElectron Transport Complex IVRNA, RibosomalRNA, ribosomal, 12S

Identifiers

PMID34634776
PMCPMC8733484

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.