Evidence map›Paper›PMID 34634680›Full record

ArticleAutonomic neuroscience : basic & clinical2021

Functional anatomy of the vagus system - Emphasis on the somato-visceral interface.

Winfried L Neuhuber, Hans-Rudolf Berthoud

Open access · greenAbstract read
In one paragraph

Article in Autonomic neuroscience : basic & clinical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 71 citations in OpenAlex.

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  5. The auricular cough reflex: lateralization, prevalence, procedural determinants, and the role of examiner handedness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
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  11. [Research progress on vagus nerve stimulation in the treatment of chronic pain].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
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  20. Novel neural pathways targeted by GLP-1R agonists and bariatric surgery.Pflugers Archiv : European journal of physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Winfried L NeuhuberInstitute of Anatomy and Cell Biology, Friedrich-Alexander University, Krankenhausstrasse 9, Erlangen, Germany. Electronic address: winfried.neuhuber@fau.de.
Hans-Rudolf BerthoudNeurobiology of Nutrition & Metabolism Department, Pennington Biomedical Research Center, Louisiana State University, 6400 Perkins Road, Baton Rouge, LA 70808, USA. Electronic address: berthohr@pbrc.edu.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEPennington Biomedical Research Center · US

Funding

Neural mechanisms controlling food intake and body weight after bariatric surgeryR01DK047348 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BERTHOUD, HANS-RUDOLF · 1994 to 2018
$5.0M
NIDDK NIH HHS R01 DK047348
6 · The paper itself

Abstract

Due to its pivotal role in autonomic networks, the vagus attracts continuous interest from both basic scientists and clinicians. In particular, recent advances in vagus nerve stimulation strategies and their application to pathological conditions beyond epilepsy provide a good opportunity to recall basic features of vagal peripheral and central anatomy. In addition to the "classical" vagal brainstem nuclei, i.e., dorsal motor nucleus, nucleus ambiguus and nucleus tractus solitarii, the spinal trigeminal and paratrigeminal nuclei come into play as targets of vagal afferents. On the other hand, the nucleus of the solitary tract receives and integrates not only visceral but also somatic afferents. Thus, the vagus system participates significantly in what may be defined as "somato-visceral interface".

Indexed as

Vagus NerveVagus Nerve StimulationAutonomic Nervous SystemBrain StemSolitary NucleusAuricular nervesDorsal motor nucleusNucleus ambiguusNucleus tractus solitariiParatrigeminal nucleusVagus nerve stimulation

Identifiers

PMID34634680
PMCPMC8627476
OpenAlexW3204932029

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.