Observational studyJournal of psychosomatic research2021
Plant-based dietary intake moderates adverse childhood experiences association with early mortality in an older Adventist cohort.
Observational study in Journal of psychosomatic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- Nutritional interventions to counteract the detrimental consequences of early-life stress.Molecular psychiatry · 2025Review
- Is trauma associated with plant-based diet choice?Appetite · 2025Article
- California provider and advocate perspectives about opportunities to optimize nutrition services and resources in the first 1000 days.Reproductive, female and child health · 2024Article
- The Stress Phenotyping Framework: A multidisciplinary biobehavioral approach for assessing and therapeutically targeting maladaptive stress physiology.Stress (Amsterdam, Netherlands) · 2024Review
- Association between adverse childhood experiences and fruit and vegetable intake among a national sample of U.S. adults.Preventive medicine reports · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundAdverse Childhood Experiences (ACEs) consistently predict poor mental and physical health as well as early all-cause mortality. Much work examines health harming behaviors that may be used to cope with ACEs associated stress responses and dysregulation. Limited research has been conducted assessing plant-based dietary intake on the ACEs and mortality relationship. We investigate moderators of the ACEs and mortality association including plant-based dietary intake.
objectiveThe purpose of this study is to examine if the association between ACEs and early mortality is potentially moderated by plant-based dietary intake.
participantsAn observational, prospective cohort study that included 9301 Seventh-day Adventists were assessed from 2006 to 2017 in the Biopsychosocial Religion and Health Study (BRHS).
methodsWe examined the potential impact of plant-based intake frequency on the ACEs and all-cause mortality relationship, while adjusting for potential confounders (e.g., demographics, health risks, mental and physical health) in a cox regression survival analysis.
resultsACEs were adversely associated with survival time (HR = 2.76, 95% CI: 1.15-6.64). Plant-based intake was associated with a reduction in the association of 4+ ACEs with early mortality (HR = 0.73, 95% CI: 0.59-0.90) above and beyond demographics, animal-based intake, physical health, mental health, BMI, exercise, and worship. We estimate that after 4+ ACEs, those eating high versus low plant-based dietary intake may live 5.4 years longer.
conclusionPlant-based dietary intake may potentially moderate the ACEs and early mortality relationship; however, observational studies cannot determine causality.
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Registered trials
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