Evidence map›Paper›PMID 34634431›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2022

End Points for Clinical Trials in Hyperoxaluria: Case Study of Patient-Focused Drug Development in a Rare Disease.

John C Lieske, Meaghan A Malley, Melissa West, Kim Hollander, Dawn S Milliner

Open access · bronzeAbstract readEditorial
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

John C LieskeDivision of Nephrology, Mayo Clinic, Rochester, Minnesota. Electronic address: Lieske.John@mayo.edu.
Meaghan A MalleyAmerican Society of Nephrology, Washington, DC.
Melissa WestAmerican Society of Nephrology, Washington, DC.
Kim HollanderOxalosis and Hyperoxaluria Foundation, New Paltz, New York.
Dawn S MillinerDivision of Nephrology, Mayo Clinic, Rochester, Minnesota.
American Society of Nephrology · USMayo Clinic · USOxalosis and Hyperoxaluria Foundation · US

Funding

Primary HyperoxaluriaU54DK083908 · NIDDK · MAYO CLINIC ROCHESTER · PI MILLINER, DAWN SCHMAUTZ · 2009 to 2018
$12.3M
Kidney Health Initiative is a public-private partnership between the American Society of Nephrology, US Food and Drug Administration and the kidney community.R18FD005283 · FDA · AMERICAN SOCIETY OF NEPHROLOGY, INC. · PI Tod Ramses Ibrahim · 2014 to 2026
$4.6M
Facilitating personalized medicine of monogenic stone patients by genetic characterizationR21TR003174 · NCATS · MAYO CLINIC ROCHESTER · PI HARRIS, PETER C., LIESKE, JOHN C · 2020 to 2021
$437k
FDA HHS R18 FD005283NCATS NIH HHS R21 TR003174NIDDK NIH HHS U54 DK083908
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HyperoxaluriaHyperoxaluria, PrimaryDrug DevelopmentFemaleHumansMaleRare Diseases

Identifiers

PMID34634431
PMCPMC11656491
OpenAlexW3207614758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.