Evidence map›Paper›PMID 34634150›Full record

ArticleClinical transplantation2022

Association of race and gender with primary caregiver relationships and eligibility for advanced heart failure therapies.

Rebecca S Steinberg, Aditi Nayak, Michael A Burke, Morgan Aldridge, S Raja Laskar, Kunal Bhatt, Lakshmi Sridharan, Mahmoud Abdou, Tamer Attia, Andrew Smith and 4 more

Abstract read
In one paragraph

Article in Clinical transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Racial and ethnic disparities in psychosocial evaluation and liver transplant waitlisting.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rebecca S SteinbergEmory University, Division of Cardiology, Atlanta, Georgia, USA.ORCID 0000-0003-4622-626X
Aditi NayakEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Michael A BurkeEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Morgan AldridgeEmory University, Division of Cardiology, Atlanta, Georgia, USA.
S Raja LaskarEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Kunal BhattEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Lakshmi SridharanEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Mahmoud AbdouEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Tamer AttiaEmory Transplant Center, Emory Healthcare, Atlanta, Georgia, USA.
Andrew SmithEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Mani DaneshmandEmory Transplant Center, Emory Healthcare, Atlanta, Georgia, USA.
J David VegaEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Divya GuptaEmory University, Division of Cardiology, Atlanta, Georgia, USA.
Alanna A MorrisEmory University, Division of Cardiology, Atlanta, Georgia, USA.ORCID 0000-0002-8033-3707

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
TCC for Health Disparties: Informing & Influencing Health Policy and PracticeU54MD008173 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI SATCHER, DAVID · 2012 to 2016
$13.4M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
Integrating Costs Into Shared Decision-Making for Heart Failure with Reduced Ejection FractionR01HS026081 · AHRQ · EMORY UNIVERSITY · PI DICKERT, NEAL WORKMAN · 2018 to 2022
$1.9M
Understanding Racial Differences in Vascular Function and Ventricular-Vascular Coupling in Heart Failure with Preserved Ejection FractionR03HL146874 · NHLBI · EMORY UNIVERSITY · PI MORRIS, ALANNA AMYRE · 2019 to 2020
$156k
AHRQ HHS R01 HS026081NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378NHLBI NIH HHS R03 HL146874NIMHD NIH HHS U54 MD008173
6 · The paper itself

Abstract

backgroundCaregiver support is considered necessary after heart transplant (HT) and left ventricular assist device (LVAD) for patients with end-stage heart failure (HF). Few studies have demonstrated how caregivers differ by gender and race, and whether that impacts therapy eligibility.

methodsWe examined caregiver relationships among 674 patients (32% women, 55% Black) evaluated at Emory University from 2011 to 2017. Therapy readiness was assessed using the Stanford Integrated Assessment for Transplant (SIPAT). Evaluation outcome according to caregiver relationship was compared using χ

resultsWomen and Black patients were less likely to have spouses as their support person (P < .001). Women were less likely to be considered eligible for advanced therapies (adjusted odds ratio [aOR] .64, 95% confidence interval [CI] .46-.89; P = .008), with Black women having lower eligibility than White women (aOR .28, 95% CI .11-.72; P = .008). Social support and SIPAT scores did not significantly influence eligibility by gender or race.

conclusionLack of caregiver support is considered a relative contraindication to advanced therapies. Type of caregiver in our cohort varied according to race and gender but did not explain differences in eligibility for advanced therapies.

Indexed as

Heart-Assist DevicesHeart FailureHeart TransplantationCaregiversFemaleHumansMaleRetrospective Studiesgenderhealth disparitiesrace-ethnicitysocial determinantssocial support

Identifiers

PMID34634150
PMCPMC8752502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.