Evidence map›Paper›PMID 34634132›Full record

ArticleCancer2022

Association between pregnancy intention and preconception health behaviors.

Hena Naz Din, David Strong, Savitri Singh-Carlson, Heather L Corliss, Sheri J Hartman, Hala Madanat, H Irene Su

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Development and validation of a comprehensive evaluation index system for preconception health behaviors in reproduc-tive-aged populations].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hena Naz DinSchool of Public Health, San Diego State University, San Diego, California.ORCID 0000-0002-0137-769X
David StrongHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California.
Savitri Singh-CarlsonSchool of Nursing, San Diego State University, San Diego, California.
Heather L CorlissSchool of Public Health, San Diego State University, San Diego, California.
Sheri J HartmanHerbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California.ORCID 0000-0002-3719-0624
Hala MadanatSchool of Public Health, San Diego State University, San Diego, California.
H Irene SuDivision of Reproductive Endocrinology and Infertility, University of California San Diego, San Diego, California.
San Diego State University · USUniversity of California San Diego · US

Funding

The Reproductive Window in Young Adult Cancer SurvivorsR01HD080952 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SU, HUI-CHUN IRENE · 2014 to 2018
$2.6M
Predictors of ovarian failure after chemotherapy in young breast cancer patientsK23HD058799 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SU, HUI-CHUN IRENE · 2009 to 2013
$546k
NICHD NIH HHS K23 HD058799NICHD NIH HHS R01 HD080952NIH HHS
6 · The paper itself

Abstract

backgroundFemale adolescent and young adult (AYA) cancer survivors face higher infertility and pregnancy risks than peers with no cancer history. Preconception health behaviors such as physical activity (PA), tobacco smoking, and alcohol intake influence reproductive outcomes. In general populations, pregnancy intention is positively associated with healthy preconception behaviors, but it has not been studied among AYA survivors. The authors hypothesized that higher pregnancy intention would be associated with healthier behaviors, especially among AYA survivors with perceived infertility risk.

methodsA cross-sectional analysis was conducted with data collected between 2013 and 2017 from 1071 female AYA survivors aged 18 to 39 years who had completed their primary cancer treatment and enrolled in an ovarian function study. Self-reported intention dimensions were measured as a pregnancy intention score (PIS) and trying now to become pregnant. Multivariable linear (PA), binary (smoking), and ordinal (alcohol use) logistic regressions were used to estimate associations between intentions and preconception behaviors, with adjustments made for demographic and cancer characteristics. Effect modification by perceived infertility risk was assessed.

resultsThe mean PIS was 1.1 (SD, 0.77) on a 0 to 2 scale (2 = high intention), and 8.9% were attempting pregnancy now. A higher PIS was associated with increased PA (β, 0.08; 95% CI, 0.11-1.04), whereas ambivalence in pregnancy intention was associated with lower alcohol consumption (odds ratio, 0.72; 95% CI, 0.55-0.95). Pregnancy intentions were not associated with smoking. Perceived infertility risk strengthened the relationship between PIS and PA (P < .05).

conclusionsPregnancy intentions were associated with some healthier preconception behaviors in AYA survivors. Medical professionals caring for AYA survivors may consider pregnancy intention screening to guide conversations on preconception health.

Indexed as

Cancer SurvivorsIntentionAdolescentAdultCross-Sectional StudiesFemaleHealth BehaviorHumansPreconception CarePregnancyYoung Adultadolescent and young adult canceralcoholfertilityphysical activitypreconceptionpregnancy intentionsmoking

Identifiers

PMID34634132
PMCPMC9546522
OpenAlexW3205171238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.