Evidence map›Paper›PMID 34634049›Full record

ArticlePloS one2021

Early life course processes leading to educational and economic attainment in young adulthood: Contributions of early socioeconomic adversity and education polygenic score.

Kandauda A S Wickrama, Catherine Walker OˋNeal, Tae Kyoung Lee, Seonhwa Lee

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kandauda A S WickramaDepartment of Human Development and Family Science, The University of Georgia, Athens, Georgia, United States of America.
Catherine Walker OˋNealDepartment of Human Development and Family Science, The University of Georgia, Athens, Georgia, United States of America.
Tae Kyoung LeeDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Seonhwa LeeDepartment of Christian Studies, Seoul Women's University, Seoul, Republic of Korea.ORCID 0000-0001-6803-9815

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
Couple Relationships and Health during Transition to Later AdulthoodR01AG043599 · NIA · UNIVERSITY OF GEORGIA · PI WICKRAMA, KA · 2014 to 2018
$2.6M
NIA NIH HHS R01 AG043599NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

The present study investigated an integrated life course model, drawn from the life course theoretical perspective, to elucidate youth's additive, cascading, and cumulative life course processes stemming from early socioeconomic adversity and education polygenic score (education PGS) as well as potential interactions between them (GxE), which contribute to subsequent young adult socioeconomic outcomes. Additionally, the independent, varying associations among social and genetic predictors, life-stage specific educational outcomes (educational achievement in adolescence and educational attainment, in later stages), and young adult economic outcomes were examined. The study used prospective, longitudinal data from the National Longitudinal Study of Adolescent and Adult Health (Add Health) with a sample of 5,728 youth of European ancestry. Early family socioeconomic adversity and individual education PGS were associated with life stage-specific educational outcomes through additive and cascading processes linked to young adults' economic outcomes (personal earnings) through a cumulative process. A GxE moderation existed between individuals' education PGS and early socioeconomic adversity at multiple life stages, explaining variation in adolescent educational outcomes. Both early socioeconomic adversity and education PGS were persistently associated with youth's educational and economic outcomes throughout the early life course. In sum, the findings based on the integrated life course model showed how additive, cascading, and cumulative processes were related and conditioned one another, generating specific life course patterns and outcomes. The findings highlight the value of incorporating molecular genetic information into longitudinal developmental life course research and provide insight into malleable characteristics and appropriate timing for interventions addressing youth developmental characteristics.

Indexed as

Educational StatusIncomeMultifactorial InheritanceAcademic SuccessAdolescentAdolescent HealthAdultFemaleGene-Environment InteractionHumansLongitudinal StudiesMaleProspective StudiesSocioeconomic FactorsYoung Adult

Identifiers

PMID34634049
PMCPMC8504765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.