Evidence map›Paper›PMID 34633812›Full record

ArticleACS infectious diseases2021

Development and Immunogenicity of a Prototype Multivalent Group B

Jeremy A Duke, Amy V Paschall, Lloyd S Robinson, Cory J Knoot, Evgeny Vinogradov, Nichollas E Scott, Mario F Feldman, Fikri Y Avci, Christian M Harding

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Mechanisms and Manifestations of Group B Streptococcus Meningitis in Newborns.Journal of the Pediatric Infectious Diseases Society · 2025
    Review
  7. Article
  8. Review
  9. Vaccines forFrontiers in immunology · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Jeremy A DukeDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Amy V PaschallDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Lloyd S RobinsonVaxNewMo, St. Louis, Missouri 63110, United States.
Cory J KnootVaxNewMo, St. Louis, Missouri 63110, United States.
Evgeny VinogradovHuman Health Therapeutics Centre, National Research Council Canada, Ottawa, ON K1A 0R6, Canada.ORCID 0000-0002-5364-1376
Nichollas E ScottDepartment of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC 3010, Australia.ORCID 0000-0003-2556-8316
Mario F FeldmanVaxNewMo, St. Louis, Missouri 63110, United States.
Fikri Y AvciDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United States.
Christian M HardingVaxNewMo, St. Louis, Missouri 63110, United States.ORCID 0000-0002-2158-3546
University of Georgia · USNational Research Council Canada · CAThe University of Melbourne · AUWashington University in St. Louis · US

Funding

Molecular Mechanisms for Carbohydrate Presentation to CD4+ T cells by MHCII PathwayR01AI123383 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2016 to 2026
$4.2M
Glycopeptide-specific helper T cells eliciting protective humoral immunity against HIV - ResubmissionR01AI152766 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2021 to 2026
$2.6M
Pn3Pase as an Effective Enzyme Therapeutic for Streptococcus Pneumoniae type 3 InfectionR41AI157287 · NIAID · PNEUMOTACTIX, LLC · PI AVCI, FIKRI Y · 2021 to 2022
$599k
Development of a bioconjugate vaccine against Group B StreptococcusR41AI142928 · NIAID · VAXNEWMO, LLC · PI FELDMAN, MARIO · 2019 to 2020
$580k
NIAID NIH HHS R01 AI123383NIAID NIH HHS R01 AI152766NIAID NIH HHS R41 AI142928NIAID NIH HHS R41 AI157287
6 · The paper itself

Abstract

Group B

Indexed as

Escherichia coliStreptococcal InfectionsAdultAntibodies, BacterialHumansInfant, NewbornStreptococcus agalactiaeVaccines, CombinedAntibodies, BacterialVaccines, Combinedbioconjugatebioconjugationcapsuleconjugate vaccinegroup B Streptococcusmultivalent

Identifiers

PMID34633812
PMCPMC8793035
OpenAlexW3206771275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.