Evidence map›Paper›PMID 34633502›Full record

ArticleZeitschrift fur Rheumatologie2022

[Visceral leishmaniasis mimicking Felty's syndrome in rheumatoid arthritis treated with methotrexate and etanercept].

Nikolas Ruffer, Nicola M Tomas, Stefan Schmiedel, Sabine Jordan, Ina Kötter

Erratum issuedAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Zeitschrift fur Rheumatologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nikolas RufferKlinik für Rheumatologie und Immunologie, Klinikum Bad Bramstedt, Oskar-Alexander-Straße 26, 24576, Bad Bramstedt, Deutschland. n.ruffer@klinikumbb.de.ORCID http://orcid.org/0000-0001-8394-969X
Nicola M TomasIII. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Stefan SchmiedelSektion Infektiologie und Tropenmedizin, I. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Sabine JordanSektion Infektiologie und Tropenmedizin, I. Medizinische Klinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
Ina KötterKlinik für Rheumatologie und Immunologie, Klinikum Bad Bramstedt, Oskar-Alexander-Straße 26, 24576, Bad Bramstedt, Deutschland.
Universität Hamburg · DEHNO Bad Bramstedt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral leishmaniasis (VL) is a chronic parasitic disease caused by pathogens of the genus Leishmania, which can mimic numerous diseases. The leading symptoms of VL (splenomegaly, pancytopenia, fever) can be misinterpreted, especially if autoantibodies are detected, and lead to the misdiagnosis of an underlying rheumatic disease (e.g. systemic lupus erythematosus, Felty's syndrome). Proinflammatory cytokines such as tumour necrosis factor alpha (TNF-α) play an important role in infection control. In this context, there are increasing reports of VL as an opportunistic infection during treatment with anti-TNF‑α agents. A case of VL mimicking Felty's syndrome in a patient with rheumatoid arthritis treated with methotrexate and etanercept is presented.

Indexed as

Arthritis, RheumatoidFelty SyndromeLeishmaniasis, VisceralEtanerceptHumansMethotrexateTumor Necrosis Factor InhibitorsEtanerceptMethotrexateTumor Necrosis Factor InhibitorsAnti-TNF-α agentLeishmania infantumOpportunistic infectionPancytopeniaTumour necrosis factor alpha

Identifiers

PMID34633502
OpenAlexW3207342042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.