ArticleBrain : a journal of neurology2021
Tonic somatosensory responses and deficits of tactile awareness converge in the parietal operculum.
Article in Brain : a journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Body ownership gates tactile awareness by reshaping the somatosensory functional connectivity.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- An HD-EEG Database to dissect Somatosensory Awareness from Task Relevance and Report.Scientific data · 2025Article
- Task Relevance Modulates Somatosensory Awareness Depending on Stimulus Intensity.The European journal of neuroscience · 2025Article
- Anatomo-functional basis of emotional and motor resonance elicited by facial expressions.Brain : a journal of neurology · 2024Article
- Simultaneous invasive and non-invasive recordings in humans: A novel Rosetta stone for deciphering brain activity.Journal of neuroscience methods · 2024Review
- Structural and functional features characterizing the brains of individuals with higher controllability of motor imagery.Scientific reports · 2024Article
- Have I Been Touched? Subjective and Objective Aspects of Tactile Awareness.Brain sciences · 2024Review
- Secondary somatosensory and posterior insular cortices: a somatomotor hub for object prehension and manipulation movements.Frontiers in integrative neuroscience · 2024Article
- Spatial proximity to others induces plastic changes in the neural representation of the peripersonal space.iScience · 2023Article
- Advances in human intracranial electroencephalography research, guidelines and good practices.NeuroImage · 2022Review
- Differential Cortico-Thalamic reorganization in Opioid-Induced hyperalgesia and neuropathic pain male rats.Neurobiology of pain (Cambridge, Mass.)Article
Corrections and comments
- Commented on by
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although clinical neuroscience and the neuroscience of consciousness have long sought mechanistic explanations of tactile-awareness disorders, mechanistic insights are rare, mainly because of the difficulty of depicting the fine-grained neural dynamics underlying somatosensory processes. Here, we combined the stereo-EEG responses to somatosensory stimulation with the lesion mapping of patients with a tactile-awareness disorder, namely tactile extinction. Whereas stereo-EEG responses present different temporal patterns, including early/phasic and long-lasting/tonic activities, tactile-extinction lesion mapping co-localizes only with the latter. Overlaps are limited to the posterior part of the perisylvian regions, suggesting that tonic activities may play a role in sustaining tactile awareness. To assess this hypothesis further, we correlated the prevalence of tonic responses with the tactile-extinction lesion mapping, showing that they follow the same topographical gradient. Finally, in parallel with the notion that visuotactile stimulation improves detection in tactile-extinction patients, we demonstrated an enhancement of tonic responses to visuotactile stimuli, with a strong voxel-wise correlation with the lesion mapping. The combination of these results establishes tonic responses in the parietal operculum as the ideal neural correlate of tactile awareness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.