Evidence map›Paper›PMID 34633127›Full record

ArticlePediatric transplantation2022

Decreased access to pediatric liver transplantation during the COVID-19 pandemic.

Sarah Kemme, Dor Yoeli, Shikha S Sundaram, Megan A Adams, Amy G Feldman

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Pediatric transplantation during the COVID-19 pandemic.World journal of transplantation · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sarah KemmeSection of Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, University of Colorado Denver School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.ORCID 0000-0002-9524-3288
Dor YoeliDivision of Transplant Surgery, Colorado Center for Transplantation Care, Research and Education, University of Colorado Denver School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.ORCID 0000-0001-6993-255X
Shikha S SundaramSection of Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, University of Colorado Denver School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.
Megan A AdamsDivision of Transplant Surgery, Colorado Center for Transplantation Care, Research and Education, University of Colorado Denver School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.ORCID 0000-0002-0148-1593
Amy G FeldmanSection of Gastroenterology, Hepatology, and Nutrition, Digestive Health Institute, University of Colorado Denver School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA.ORCID 0000-0003-4021-5615
Children's Hospital Colorado · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Institutional Training Grant in Pediatric GastroenterologyT32DK067009 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI RONALD J. SOKOL, Edwin Fulco de Zoeten · 2005 to 2026
$7.1M
Improving Immunization Rates in Transplant Candidates Through the Use of a Health Information Technology ToolK08HS026510 · AHRQ · UNIVERSITY OF COLORADO DENVER · PI FELDMAN, AMY · 2019 to 2023
$742k
Agency for Healthcare Research and Quality 1K08 HS026510-01A1AHRQ HHS K08 HS026510Foundation for the National Institutes of Health T32 DK067009-15NCATS NIH HHS UL1 TR002535NIDDK NIH HHS T32 DK067009
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has affected all aspects of the US healthcare system, including liver transplantation. The objective of this study was to understand national changes to pediatric liver transplantation during COVID-19.

methodsUsing SRTR data, we compared waitlist additions, removals, and liver transplantations for pre-COVID-19 (March-November 2016-2019), early COVID-19 (March-May 2020), and late COVID-19 (June-November 2020).

resultsWaitlist additions decreased by 25% during early COVID-19 (41.3/month vs. 55.4/month, p < .001) with black candidates most affected (p = .04). Children spent longer on the waitlist during early COVID-19 compared to pre-COVID-19 (140 vs. 96 days, p < .001). There was a 38% decrease in liver transplantations during early COVID-19 (IRR 0.62, 95% CI 0.49-0.78), recovering to pre-pandemic rates during late COVID-19 (IRR 1.03, NS), and no change in percentage of living and deceased donors. White children had a 30% decrease in overall liver transplantation but no change in living donor liver transplantation (IRR 0.7, 95% CI 0.50-0.95; IRR 0.96, NS), while non-white children had a 44% decrease in overall liver transplantation (IRR 0.56, 95% CI 0.40-0.77) and 81% decrease in living donor liver transplantation (IRR 0.19, 95% CI 0.02-0.76).

conclusionsThe COVID-19 pandemic decreased access to pediatric liver transplantation, particularly in its early stage. There were no regional differences in liver transplantation during COVID-19 despite the increased national sharing of organs. While pediatric liver transplantation has resumed pre-pandemic levels, ongoing racial disparities must be addressed.

Indexed as

COVID-19AdolescentChildChild, PreschoolFemaleHealthcare DisparitiesHealth Services AccessibilityHumansInfantInfant, NewbornLiver TransplantationLiving DonorsMaleRegistriesRetrospective StudiesUnited Statesaccess to careCOVID-19outcomepediatric liver transplantation

Identifiers

PMID34633127
PMCPMC8646490
OpenAlexW3206408907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.